Recent improvements in proteomics technologies have fundamentally altered our capacities
to characterize human biology. There is an ever-growing interest in using these novel …

Type 1 diabetes (T1D) is a chronic autoimmune disorder characterised by an autoimmune
response specifically mounted against the insulin-producing beta cells. Within the islet, high …

Despite immense interest in biomarker applications of extracellular vesicles (EVs) from
blood, our understanding of circulating EVs under physiological conditions in healthy …

Non-tuberculous mycobacterial pulmonary disease (NTM-PD) is a chronic progressive lung
disease that is increasing in incidence. Host genetic factors are associated with NTM-PD …

Introduction Double C2-like domain beta (DOC2B) is a vesicle priming protein critical for
glucose-stimulated insulin secretion in β-cells. Individuals with type 1 diabetes (T1D) have …

Background: In this study, we investigated the role of extracellular vesicles (EVs) in the
pathogenesis of Congenital Zika Syndrome (CZS). Previous studies have highlighted the …

The technical difficulty of separating extracellular vesicles (EVs) from plasma proteins in
human blood presents a significant hurdle in EV research, particularly during nano ultra …

Extracellular vesicles (EVs) carry diverse biomolecules derived from their parental cells,
making their components excellent biomarker candidates. However, purifying EVs is a major …

Extracellular vesicles (EVs), nanoscale vesicles that are secreted by cells, are critical
mediators of intercellular communication and play a crucial role in diverse pathologies such …

Extracellular vesicles (EVs) in blood plasma offer a valuable reservoir of intracellular cellular
cargo, making them a promising source of liquid based biomarkers. The molecular cargo of …