Understanding the vertebrate immune system: insights from the reptilian perspective

LM Zimmerman, LA Vogel… - Journal of Experimental …, 2010 - journals.biologists.com
Reptiles are ectothermic amniotes, providing the key link between ectothermic anamniotic
fishes and amphibians, and endothermic amniotic birds and mammals. A greater …

The changing biological roles of melatonin during evolution: from an antioxidant to signals of darkness, sexual selection and fitness

DX Tan, R Hardeland, LC Manchester… - Biological …, 2010 - Wiley Online Library
Melatonin is a molecule present in a multitude of taxa and may be ubiquitous in organisms. It
has been found in bacteria, unicellular eukaryotes, macroalgae, fungi, plants and animals. A …

Discovery of a unique Ig heavy-chain isotype (IgT) in rainbow trout: Implications for a distinctive B cell developmental pathway in teleost fish

JD Hansen, ED Landis, RB Phillips - … of the National Academy of Sciences, 2005 - pnas.org
During the analysis of Ig superfamily members within the available rainbow trout
(Oncorhynchus mykiss) EST gene index, we identified a unique Ig heavy-chain (IgH) …

[HTML][HTML] Amphibian metamorphosis

DD Brown, L Cai - Developmental biology, 2007 - Elsevier
JF Gudernatsch, an anatomist at Cornell Medical School, traveled by ship to the Naples
Zoological Station in the summer of 1910. He took along various mammalian organs …

Review of the amphibian immune response to chytridiomycosis, and future directions

LF Grogan, J Robert, L Berger, LF Skerratt… - Frontiers in …, 2018 - frontiersin.org
The fungal skin disease, chytridiomycosis (caused by Batrachochytrium dendrobatidis and
B. salamandrivorans), has caused amphibian declines and extinctions globally since its …

Comparative and developmental study of the immune system in Xenopus

J Robert, Y Ohta - Developmental Dynamics, 2009 - Wiley Online Library
Xenopus laevis is the model of choice for evolutionary, comparative, and developmental
studies of immunity, and invaluable research tools including MHC‐defined clones, inbred …

Microbiota and mucosal immunity in amphibians

BM Colombo, T Scalvenzi, S Benlamara… - Frontiers in …, 2015 - frontiersin.org
We know that animals live in a world dominated by bacteria. In the last 20 years, we have
learned that microbes are essential regulators of mucosal immunity. Bacteria, archeas, and …

450 million years in the making: map** the evolutionary foundations of germinal centers

H Matz, H Dooley - Frontiers in immunology, 2023 - frontiersin.org
Germinal centers (GCs) are distinct microanatomical structures that form in the secondary
lymphoid organs of endothermic vertebrates (ie, mammals and some birds). Within GCs, B …

Evolution of the inflammatory response in vertebrates: fish TNF-α is a powerful activator of endothelial cells but hardly activates phagocytes

FJ Roca, I Mulero, A López-Muñoz… - The Journal of …, 2008 - journals.aai.org
TNF-α is conserved in all vertebrate classes and has been identified in all taxonomic groups
of teleost fish. However, its biological activities and its role in infection are largely unknown …

Restructuring of the amphibian gut microbiota through metamorphosis

KD Kohl, TL Cary, WH Karasov… - Environmental …, 2013 - Wiley Online Library
Vertebrates maintain complex symbioses with a diverse community of microbes residing
within their guts. The microbial players in these symbioses differ between major taxa of …