Compelling preclinical and clinical evidence supports a pathophysiological connection
between Alzheimer's disease (AD) and diabetes. Altered metabolism, inflammation, and …

Human studies are reviewed concerning whether “aging”-related mechanisms contribute to
Alzheimer's disease (AD) pathogenesis. AD is defined by specific neuropathology: neuritic …

One of the challenges of managing older adults with diabetes is the individualization of care
in people with multiple comorbid conditions. Although macrovascular and microvascular …

Methods Participants without dementia aged 55–90 years from the Cognition and Diabetes
in Older Tasmanians (CDOT) study underwent brain MRI (ventricular and total brain volume) …

Background A number of prospective cohort studies have examined the association
between intelligence in childhood or youth and life expectancy in adulthood; however, the …

Background Mild cognitive impairment (MCI), a common condition among the elderly, is
defined as a deterioration of memory, attention, and cognitive function that exceeds what …

People with diabetes mellitus are at increased risk of cognitive dysfunction and dementia.
This review explores the nature and severity of cognitive changes in patients with type 2 …

Background Type 2 diabetes increases the risk for dementia, but whether it affects cognition
before old age is unclear. We investigated whether duration of diabetes in late midlife and …

Diabetes (diagnosed or undiagnosed) affects 10.9 million US adults aged 65 years and
older. Almost 8 in 10 have some form of dysglycemia, according to tests for fasting glucose …

Metabolic syndrome is a cluster of cardiovascular risk factors defined by the presence of
abdominal obesity, glucose intolerance, hypertension and/or dyslipidemia. It is a major …