States of oral health and disease reflect the compositional and functional capacities of, as
well as the interspecies interactions within, the oral microbiota. The oral cavity exists as a …

Objectives To review the application of omics technologies in the field of cariology research
and provide critical insights into the emerging opportunities and challenges. Data & Sources …

Objective Microbiota comparisons between healthy and diseased dental tissues have
accentuated the importance of cultivating and identifying bacterial species that play a role in …

Objective To review published oral microbiome studies and create a comprehensive list of
bacterial species found in saliva and dental plaque among healthy children and adults …

Caries is one of the most prevalent infectious diseases worldwide and is driven by the
dysbiosis of dental biofilms adhering to tooth surfaces. The pits and fissured surfaces are the …

Early childhood caries (ECC) is the most common chronic infectious oral disease in
preschool children worldwide. It is closely related to the caries activity (CA) of children …

Objectives: In light of recent technological advances in Next-generation sequencing (NGS)
and the accumulation of large, publicly available oral microbiome datasets, the need for …

Maintaining a symbiotic oral microbiota is essential for oral and dental health, and host
genetic factors may affect the composition or function of the oral microbiota through a range …

It has been questioned whether Streptococcus mutans can still be considered the major
etiological agent for caries. The main argument is that most evidence has been based on …

Background Streptococcus mutans is recognized as a key pathogen responsible for the
development of dental caries. With the advancement of research on dental caries, the …