Recent insights into the pathophysiologic underlying mechanisms of obesity have led to the
discovery of several promising drug targets and novel therapeutic strategies to address the …

In spike-timing-dependent plasticity (STDP), the order and precise temporal interval
between presynaptic and postsynaptic spikes determine the sign and magnitude of long …

Synaptic plasticity is the capacity of a preexisting connection between two neurons to
change in strength as a function of neural activity. Because synaptic plasticity is the major …

Among the many signalling lipids, endocannabinoids are increasingly recognized for their
important roles in neuronal and glial development. Recent experimental evidence suggests …

In primary sensory neocortical areas of mammals, the distribution of sensory receptors is
mapped with topographic precision and amplification in proportion to the peripheral receptor …

Endocannabinoid mediated spike timing–dependent depression (t-LTD) is crucially involved
in the development of the sensory neocortex. t-LTD at excitatory synapses in the develo** …

Cannabinoids, the active components of cannabis (Cannabis sativa) extracts, have attracted
the attention of human civilizations for centuries, much earlier than the discovery and …

As more states and countries legalize medical and/or adult recreational marijuana use, the
incidences of prenatal cannabis exposure (PCE) will likely increase. While young people …

Long-term synaptic plasticity is a major cellular substrate for learning, memory, and
behavioral adaptation. Although early examples of long-term synaptic plasticity described a …

Astrocytes are emerging as integral functional components of synapses, responding to
synaptically released neurotransmitters and regulating synaptic transmission and plasticity …