Use of brain biomechanical models for monitoring impact exposure in contact sports

S Ji, M Ghajari, H Mao, RH Kraft… - Annals of Biomedical …, 2022 - Springer
Head acceleration measurement sensors are now widely deployed in the field to monitor
head kinematic exposure in contact sports. The wealth of impact kinematics data provides …

An anatomically detailed and personalizable head injury model: Significance of brain and white matter tract morphological variability on strain

X Li, Z Zhou, S Kleiven - Biomechanics and modeling in mechanobiology, 2021 - Springer
Finite element head (FE) models are important numerical tools to study head injuries and
develop protection systems. The generation of anatomically accurate and subject-specific …

Identifying Factors Associated with Head Impact Kinematics and Brain Strain in High School American Football via Instrumented Mouthguards

NJ Cecchi, AG Domel, Y Liu, E Rice, R Lu… - Annals of biomedical …, 2021 - Springer
Repeated head impact exposure and concussions are common in American football.
Identifying the factors associated with high magnitude impacts aids in informing sport policy …

In vivo estimates of axonal stretch and 3D brain deformation during mild head impact

AK Knutsen, AD Gomez, M Gangolli, WT Wang… - Brain multiphysics, 2020 - Elsevier
The rapid deformation of brain tissue in response to head impact can lead to traumatic brain
injury. In vivo measurements of brain deformation during non-injurious head impacts are …

Displacement-and strain-based discrimination of head injury models across a wide range of blunt conditions

W Zhao, S Ji - Annals of biomedical engineering, 2020 - Springer
Successful validation of a head injury model is critical to ensure its biofidelity. However,
there is an ongoing debate on what experimental data are suitable for model validation …

[HTML][HTML] A quantitative relationship between rotational head kinematics and brain tissue strain from a 2-D parametric finite element analysis

RW Carlsen, AL Fawzi, Y Wan, H Kesari, C Franck - Brain Multiphysics, 2021 - Elsevier
Given the complex nature of traumatic brain injury (TBI), assessment of injury risk directly
from kinematic measures of head motion remains a challenge. Despite this challenge …

Brain strain from motion of sparse markers

Z Zhou, X Li, S Kleiven, WN Hardy - 2020 - sae.org
Brain strain secondary to head impact or inertial loading is closely associated with
pathologic observations in the brain. The only experimental brain strain dataset under …

The White Matter Fiber Tract Deforms Most in the Perpendicular Direction During In Vivo Volunteer Impacts

Z Zhou, C Olsson, TC Gasser, X Li… - Journal of …, 2024 - liebertpub.com
White matter (WM) tract-related strains are increasingly used to quantify brain mechanical
responses, but their dynamics in live human brains during in vivo impact conditions remain …

Predictive factors of kinematics in traumatic brain injury from head impacts based on statistical interpretation

X Zhan, Y Li, Y Liu, AG Domel, HV Alizadeh… - Annals of biomedical …, 2021 - Springer
Brain tissue deformation resulting from head impacts is primarily caused by rotation and can
lead to traumatic brain injury. To quantify brain injury risk based on measurements of …

Toward a comprehensive delineation of white matter tract-related deformation

Z Zhou, X Li, Y Liu, M Fahlstedt, M Georgiadis… - Journal of …, 2021 - liebertpub.com
Finite element (FE) models of the human head are valuable instruments to explore the
mechanobiological pathway from external loading, localized brain response, and resultant …