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A systematic review of the valproic-acid-induced rodent model of autism
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterised by
repetitive behaviours, cognitive rigidity/inflexibility, and social-affective impairment …
repetitive behaviours, cognitive rigidity/inflexibility, and social-affective impairment …
Prenatal valproate in rodents as a tool to understand the neural underpinnings of social dysfunctions in autism spectrum disorder
AM Tartaglione, S Schiavi, G Calamandrei, V Trezza - Neuropharmacology, 2019 - Elsevier
Impairments in social interaction and verbal and non verbal communication are among the
main features of Autism Spectrum Disorder (ASD). The causes of ASD are still unknown but …
main features of Autism Spectrum Disorder (ASD). The causes of ASD are still unknown but …
Impaired repair of DNA damage is associated with autistic-like traits in rats prenatally exposed to valproic acid
M Servadio, A Manduca, F Melancia, L Leboffe… - European …, 2018 - Elsevier
Prenatal exposure to the antiepileptic and mood stabilizer valproic acid (VPA) is an
environmental risk factor for autism spectrum disorders (ASD), although recent …
environmental risk factor for autism spectrum disorders (ASD), although recent …
Valproic acid exposure impairs ultrasonic communication in infant, adolescent and adult rats
K Gzielo, A Potasiewicz, M Hołuj, E Litwa… - European …, 2020 - Elsevier
Persistent deficits of social communication are a hallmark of autism spectrum disorders
(ASD). Communication disabilities can be experimentally modeled using rodents' ultrasonic …
(ASD). Communication disabilities can be experimentally modeled using rodents' ultrasonic …
The Notch1/Hes1 signaling pathway affects autophagy by adjusting DNA methyltransferases expression in a valproic acid-induced autism spectrum disorder model
Y Li, L Ma, Y Deng, Z Du, B Guo, J Yue, X Liu… - …, 2023 - Elsevier
As a pervasive neurodevelopmental disease, autism spectrum disorder (ASD) is caused by
both hereditary and environmental elements. Research has demonstrated the functions of …
both hereditary and environmental elements. Research has demonstrated the functions of …
Chronic ambient ozone exposure aggravates autism-like symptoms in a susceptible mouse model
W Ling, Z Ren, W Wang, D Lu, Q Zhou… - Environmental …, 2023 - ACS Publications
Although there is evidence that exposure to ground-level ozone (O3) may cause an
increased risk of neurological disorders (eg, autistic spectrum disorder), low-dose chronic …
increased risk of neurological disorders (eg, autistic spectrum disorder), low-dose chronic …
Effects of PM2.5 and gases exposure during prenatal and early-life on autism–like phenotypes in male rat offspring
Background Epidemiological studies have reported associations between elevated air
pollution and autism spectrum disorders (ASD). However, we hypothesized that exposure to …
pollution and autism spectrum disorders (ASD). However, we hypothesized that exposure to …
Strain differences in the susceptibility to the gut–brain axis and neurobehavioural alterations induced by maternal immune activation in mice
There is a growing realization that the severity of the core symptoms of autism spectrum
disorders and schizophrenia is associated with gastrointestinal dysfunction. Nonetheless …
disorders and schizophrenia is associated with gastrointestinal dysfunction. Nonetheless …
Consequences of prenatal exposure to valproic acid in the socially monogamous prairie voles
Environmental risk factors contribute to autism spectrum disorders (ASD) etiology. In
particular, prenatal exposure to the highly teratogenic anticonvulsant valproic acid (VPA) …
particular, prenatal exposure to the highly teratogenic anticonvulsant valproic acid (VPA) …
Single administration of resveratrol improves social behavior in adult mouse models of autism spectrum disorder
S Hidema, S Kikuchi, R Takata, T Yanai… - Bioscience …, 2020 - academic.oup.com
Resveratrol (RSV) is a natural polyphenol present in grapes, the skin of peanuts, and
several other plants with many health benefits. Autism spectrum disorder (ASD) is a …
several other plants with many health benefits. Autism spectrum disorder (ASD) is a …