Neurotrophic factor BDNF, physiological functions and therapeutic potential in depression, neurodegeneration and brain cancer

L Colucci-D'Amato, L Speranza, F Volpicelli - International journal of …, 2020 - mdpi.com
Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively
studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin …

Muscle–organ crosstalk: the emerging roles of myokines

MCK Severinsen, BK Pedersen - Endocrine reviews, 2020 - academic.oup.com
Physical activity decreases the risk of a network of diseases, and exercise may be
prescribed as medicine for lifestyle-related disorders such as type 2 diabetes, dementia …

Physical activity and muscle–brain crosstalk

BK Pedersen - Nature Reviews Endocrinology, 2019 - nature.com
Neurological and mental illnesses account for a considerable proportion of the global
burden of disease. Exercise has many beneficial effects on brain health, contributing to …

[HTML][HTML] Effect of aerobic exercise on hippocampal volume in humans: a systematic review and meta-analysis

J Firth, B Stubbs, D Vancampfort, F Schuch… - Neuroimage, 2018 - Elsevier
Hippocampal volume increase in response to aerobic exercise has been consistently
observed in animal models. However, the evidence from human studies is equivocal. We …

Exercise as medicine–evidence for prescribing exercise as therapy in 26 different chronic diseases

BK Pedersen, B Saltin - … journal of medicine & science in sports, 2015 - Wiley Online Library
This review provides the reader with the up‐to‐date evidence‐based basis for prescribing
exercise as medicine in the treatment of 26 different diseases: psychiatric diseases …

EPA guidance on physical activity as a treatment for severe mental illness: a meta-review of the evidence and Position Statement from the European Psychiatric …

B Stubbs, D Vancampfort, M Hallgren, J Firth… - European …, 2018 - cambridge.org
Physical activity (PA) may be therapeutic for people with severe mental illness (SMI) who
generally have low PA and experience numerous life style-related medical complications …

Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium

TGM van Erp, DP Hibar, JM Rasmussen… - Molecular …, 2016 - nature.com
The profile of brain structural abnormalities in schizophrenia is still not fully understood,
despite decades of research using brain scans. To validate a prospective meta-analysis …

Aerobic exercise improves cognitive functioning in people with schizophrenia: a systematic review and meta-analysis

J Firth, B Stubbs, S Rosenbaum… - Schizophrenia …, 2017 - academic.oup.com
Cognitive deficits are pervasive among people with schizophrenia and treatment options are
limited. There has been an increased interest in the neurocognitive benefits of exercise, but …

Exercise as medicine for mental and substance use disorders: a meta-review of the benefits for neuropsychiatric and cognitive outcomes

G Ashdown-Franks, J Firth, R Carney, AF Carvalho… - Sports Medicine, 2020 - Springer
Background Exercise may improve neuropsychiatric and cognitive symptoms in people with
mental disorders, but the totality of the evidence is unclear. We conducted a meta-review of …

[HTML][HTML] Thirty years of research on negative symptoms of schizophrenia: a scientometric analysis of hotspots, bursts, and research trends

M Sabe, C Chen, N Perez, M Solmi, A Mucci… - Neuroscience & …, 2023 - Elsevier
Research on negative symptoms of schizophrenia has received renewed interest since the
1980s. A scientometric analysis that objectively maps scientific knowledge, with changes in …