In the context of the escalating global health challenge posed by Alzheimer's disease (AD),
this comprehensive review considers the potential of melatonin in both preventive and …

Melatonin and novel melatonin-based therapies such as melatonin-containing hybrid
molecules, melatonin analogues, and melatonin derivatives have been investigated as …

Melatonin, N-acetyl-5-hydroxytryptamine, is a hormone that synchronizes the internal
environment with the photoperiod. It is synthesized in the pineal gland and greatly depends …

Melatonin is a hormone secreted by the pineal gland, it can be associated with circadian
rhythms, aging and neuroprotection. Melatonin levels are decreased in sporadic Alzheimer's …

The identification of protective agents for the treatment of neurodegenerative diseases is the
mainstay therapeutic goal to modify the disease course and arrest the irreversible disability …

ABSTRACT Melatonin (N-acetyl-5-methoxytryptamine) is an indoleamine secreted by the
pineal gland during the dark phase of the photoperiod. Its main function is the …

There are currently no effective treatments to prevent, halt, or reverse Alzheimer's disease
(AD), the most common cause of dementia in older adults. Melatonin, a relatively harmless …

A reduction in melatonin function contributes to the acceleration of Alzheimer's disease (AD),
and understanding the molecular processes of melatonin-related signaling is critical for …

Preclinical and clinical evidence supports melatonin and its analogues as potential
treatment for diseases involving cognitive deficit such as Alzheimer's disease. In this work …

Cognitive impairment (CI) can seriously affect people's mental and physical health. Yuanzhi
San (YZS) is a classic prescription for treating CI, but the mechanisms need further …