The biologically relevant coordination chemistry of iron and nitric oxide: electronic structure and reactivity

N Lehnert, E Kim, HT Dong, JB Harland… - Chemical …, 2021 - ACS Publications
Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

Radical causes of cancer

SP Hussain, LJ Hofseth, CC Harris - Nature Reviews Cancer, 2003 - nature.com
Free radicals are ubiquitous in our body and are generated by normal physiological
processes, including aerobic metabolism and inflammatory responses, to eliminate invading …

[PDF][PDF] Nitric oxide and superoxide in inflammation

T Guzik, R Korbut, T Adamek-Guzik - J physiol pharmacol, 2003 - jpp.krakow.pl
Nitric oxide (NO) and reactive oxygen species exert multiple modulating effects on
inflammation and play a key role in the regulation of immune responses. They affect virtually …

Chronic inflammation and cancer.

E Shacter, SA Weitzman - Oncology (Williston Park, NY), 2002 - europepmc.org
A substantial body of evidence supports the conclusion that chronic inflammation can
predispose an individual to cancer, as demonstrated by the association between chronic …

Cellular and oxidative mechanisms associated with interleukin-6 signaling in the vasculature

SP Didion - International journal of molecular sciences, 2017 - mdpi.com
Reactive oxygen species, particularly superoxide, promote endothelial dysfunction and
alterations in vascular structure. It is increasingly recognized that inflammatory cytokines …

Inducible nitric oxide synthase and inflammatory diseases

R Zamora, Y Vodovotz, TR Billiar - Molecular medicine, 2000 - Springer
Nitric oxide (NO) is a colorless gas at room temperature and one of the simplest molecules
known, yet it has been implicated in a wide variety of regulatory mechanisms ranging from …

The endothelium, Part I: Multiple functions of the endothelial cells--focus on endothelium-derived vasoactive mediators

M Félétou - 2011 - books.google.com
The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the
blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in …

Nitric oxide in mucosal defense: a little goes a long way

JL Wallace, MJS Miller - Gastroenterology, 2000 - Elsevier
Nitric oxide (NO) is now recognized as an important modulator of an enormous number of
physiological processes, ranging from blood pressure regulation to neuronal transmission to …

Biology of nitrogen oxides in the gastrointestinal tract

JO Lundberg, E Weitzberg - Gut, 2013 - gut.bmj.com
Throughout the human gastrointestinal tract a variety of reactive nitrogen oxides are
continuously formed as a result of a complex interplay between the host, commensal …

Insulin resistance and the endothelium

WA Hsueh, CJ Lyon, MJ Quiñones - The American journal of medicine, 2004 - Elsevier
There is increasing evidence of a parallel progression between insulin resistance and
endothelial dysfunction, suggesting a close association between insulin action and the …