The clinical responses observed following treatment with immune checkpoint inhibitors
(ICIs) support immunotherapy as a potential anticancer treatment. However, a large …

Osteosarcomas (OSs) are bone tumors most commonly found in pediatric and adolescent
patients characterized by high risk of metastatic progression and recurrence after therapy …

Among the various immunological and non-immunological tumor-promoting activities of
myeloid-derived suppressor cells (MDSCs), their immunosuppressive capacity remains a …

Myeloid cells are the most abundant nucleated haematopoietic cells in the human body and
are a collection of distinct cell populations with many diverse functions. The three groups of …

Cancer therapy has developed around the concept of killing, or stop** the growth of, the
cancer cells. Molecularly targeted therapy is the modern expression of this paradigm …

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature
myeloid cells that suppress innate and adaptive immunity. MDSCs are present in many …

Myeloid‐derived suppressor cells (MDSC) and regulatory T (Treg) cells are major
components of the immune suppressive tumour microenvironment (TME). Both cell types …

Myeloid-derived suppressor cells are a heterogeneous group of pathologically activated
immature cells that play a major role in the negative regulation of the immune response in …

Of the multiple unique stromal cell types common to solid tumors, tumor-associated
macrophages (TAMs) are significant for fostering tumor progression. The protumor …

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells that
expand during cancer, inflammation and infection, and that have a remarkable ability to …