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HIV‐related immune activation and inflammation: current understanding and strategies
T Lv, W Cao, T Li - Journal of immunology research, 2021 - Wiley Online Library
Although antiretroviral therapy effectively controls human immunodeficiency virus (HIV)
replication, a residual chronic immune activation/inflammation persists throughout the …
replication, a residual chronic immune activation/inflammation persists throughout the …
Cytokines and chemokines at the crossroads of neuroinflammation, neurodegeneration, and neuropathic pain
G Ramesh, AG MacLean… - Mediators of inflammation, 2013 - Wiley Online Library
Cytokines and chemokines are proteins that coordinate the immune response throughout
the body. The dysregulation of cytokines and chemokines is a central feature in the …
the body. The dysregulation of cytokines and chemokines is a central feature in the …
Viral encephalitis and neurologic diseases: focus on astrocytes
Neurotropic RNA virus infections cause a major neurological disease burden. Due to the
morbidity and mortality rates of viral encephalitides worldwide, there is a need to develop …
morbidity and mortality rates of viral encephalitides worldwide, there is a need to develop …
Transcription factor NF-κB: an update on intervention strategies
The nuclear factor (NF)-κB family of transcription factors are ubiquitous and pleiotropic
molecules that regulate the expression of more than 150 genes involved in a broad range of …
molecules that regulate the expression of more than 150 genes involved in a broad range of …
Neuroinflammation and EIF2 signaling persist despite antiretroviral treatment in an hiPSC tri-culture model of HIV infection
SK Ryan, MV Gonzalez, JP Garifallou, FC Bennett… - Stem cell reports, 2020 - cell.com
HIV-associated neurocognitive disorders (HAND) affect over half of HIV-infected individuals,
despite antiretroviral therapy (ART). Therapeutically targetable mechanisms underlying …
despite antiretroviral therapy (ART). Therapeutically targetable mechanisms underlying …
Involvement of metabotropic glutamate receptor 5, AKT/PI3K signaling and NF-κB pathway in methamphetamine-mediated increase in IL-6 and IL-8 expression in …
A Shah, PS Silverstein, DP Singh, A Kumar - Journal of neuroinflammation, 2012 - Springer
Methamphetamine (MA) is one of the commonly used illicit drugs and the central nervous
system toxicity of MA is well documented. The mechanisms contributing to this toxicity have …
system toxicity of MA is well documented. The mechanisms contributing to this toxicity have …
HIV-associated synaptic degeneration
Human immunodeficiency virus (HIV) infection induces neuronal injuries, with almost 50% of
infected individuals develo** HIV-associated neurocognitive disorders (HAND). Although …
infected individuals develo** HIV-associated neurocognitive disorders (HAND). Although …
[HTML][HTML] The HIV-1 transgenic rat model of neuroHIV
M Vigorito, KP Connaghan, SL Chang - Brain, behavior, and immunity, 2015 - Elsevier
Despite the ability of current combination anti-retroviral therapy (cART) to limit the
progression of HIV-1 to AIDS, HIV-positive individuals continue to experience neuroHIV in …
progression of HIV-1 to AIDS, HIV-positive individuals continue to experience neuroHIV in …
The interplay of HIV and autophagy in early infection
R Cabrera-Rodríguez, S Pérez-Yanes… - Frontiers in …, 2021 - frontiersin.org
HIV/AIDS is still a global threat despite the notable efforts made by the scientific and health
communities to understand viral infection, to design new drugs or to improve existing ones …
communities to understand viral infection, to design new drugs or to improve existing ones …
HIV gp120-and methamphetamine-mediated oxidative stress induces astrocyte apoptosis via cytochrome P450 2E1
Abstract HIV-1 glycoprotein 120 (gp120) is known to cause neurotoxicity via several
mechanisms including production of proinflammatory cytokines/chemokines and oxidative …
mechanisms including production of proinflammatory cytokines/chemokines and oxidative …