Quantitative MRI provides biophysical measures of the microstructural integrity of the CNS,
which can be compared across CNS regions, patients, and centres. In patients with multiple …

Dynamic macrostructural and microstructural changes take place from the mid-fetal stage to
2 years after birth. Delineating structural changes of the brain during early development …

For the past 25 years, the field of neuroimaging has witnessed the development of several
software packages for processing multi-parametric magnetic resonance imaging (mpMRI) to …

Objective Conventional magnetic resonance imaging (MRI) of the multiple sclerosis spinal
cord is limited by low specificity regarding the underlying pathological processes, and new …

Multiple sclerosis is characterized by inflammatory activity that results in destruction of the
myelin sheaths that enwrap axons. The currently available medications for multiple sclerosis …

Training during a sensitive period in development may have greater effects on brain
structure and behavior than training later in life. Musicians are an excellent model for …

In this article we review recent research on diffusion tensor imaging (DTI) of white matter
(WM) integrity and the implications for age-related differences in cognition. Neurobiological …

Diffusion tensor imaging has been used extensively as a research tool to understand the
structural changes associated with white matter pathology. Using water diffusion as the …

The greatest unmet need in multiple sclerosis (MS) are treatments that delay, prevent or
reverse progression. One of the most tractable strategies to achieve this is to therapeutically …

Abstract Background Autism Spectrum Disorder (ASD) symptoms have been hypothesized
to result from altered brain connectivity. The 'disconnectivity'hypothesis has been used to …