The world population is ageing rapidly. As society ages, the incidence of physical limitations
is dramatically increasing, which reduces the quality of life and increases healthcare …

The number of adults 65 years and older is increasing worldwide and will represent the 20%
of the population by 2030. Half of them will suffer from obesity. The decline in muscle mass …

Aim Exercise is one of the most important components in frailty prevention and treatment.
Therefore, we systematically reviewed the effect of resistance training (RT) alone or …

Background The combination of low-load resistance training with blood flow restriction
(BFR) has recently been shown to promote muscular adaptations in various populations. To …

Receptor activator of NF-κB ligand (RANKL) activates, while osteoprotegerin (OPG) inhibits,
osteoclastogenesis. A neutralizing Ab against RANKL, denosumab, improves bone strength …

Skeletal muscle is a highly plastic tissue that plays a central role in human health and
disease. Aging is associated with a decrease in muscle mass and function (sarcopenia) that …

Abnormalities in body composition can occur at any body weight. Low muscle mass is a
predictor of poor morbidity and mortality and occurs in several populations. This narrative …

The purpose of this study was to stratify an older adult population for subsequent
interventions based on functional ability, and to estimate prevalence, characteristics and …

Due to the demographic changes and the increasing awareness of the role of physical
function, mobility in older age is becoming an important topic. Mobility limitations have been …

The triad of vascular impairment, muscle atrophy, and cognitive decline represents critical
age-related conditions that significantly impact health. Vascular impairment disrupts blood …