Lysophosphatidylcholines are a group of bioactive lipids heavily investigated in the context
of inflammation and atherosclerosis development. While present in plasma during …

Pulmonary arterial hypertension (PAH) is characterized by impaired regulation of pulmonary
hemodynamics and vascular growth. Alterations of metabolism and bioenergetics are …

Background COVID-19 is a multi-system disorder with high variability in clinical outcomes
among patients who are admitted to hospital. Although some cytokines such as interleukin …

Pulmonary arterial hypertension (PAH) is a rare disease characterized by pulmonary
vascular remodeling leading to right heart failure and death. To date, despite the three …

The endothelium is a monolayer of cells lining the inner blood vessels. Endothelial cells
(ECs) play indispensable roles in angiogenesis, homeostasis, and immune response under …

Pulmonary arterial hypertension (PAH) is a progressive disease characterized by elevated
pulmonary arterial pressure due to increased pulmonary vascular resistance, secondary to …

Aortic dissection (AD) is a disease with high mortality and lacks effective drug treatment.
Recent studies have shown that the development of AD is closely related to glucose …

Research during the past decades has yielded numerous insights into the presence and
function of lactate in the body. Lactate is primarily produced via glycolysis and plays special …

Background Identification of metabolomics profile in subjects with different blood pressure,
including normal blood pressure, elevated blood pressure, stage 1 hypertension, and stage …

Although the genetic origins underpinning congenital heart disease (CHD) have been
extensively studied, genes, by themselves, do not entirely predict phenotypes, which result …