New developments in RiPP discovery, enzymology and engineering

M Montalbán-López, TA Scott, S Ramesh… - Natural product …, 2021 - pubs.rsc.org
Covering: up to June 2020 Ribosomally-synthesized and post-translationally modified
peptides (RiPPs) are a large group of natural products. A community-driven review in 2013 …

Structural and chemical biology of terpenoid cyclases

DW Christianson - Chemical reviews, 2017 - ACS Publications
The year 2017 marks the twentieth anniversary of terpenoid cyclase structural biology: a trio
of terpenoid cyclase structures reported together in 1997 were the first to set the foundation …

Terpenoid synthase structures: a so far incomplete view of complex catalysis

Y Gao, RB Honzatko, RJ Peters - Natural product reports, 2012 - pubs.rsc.org
Covering: up to February 2012 The complexity of terpenoid natural products has drawn
significant interest, particularly since their common (poly) isoprenyl origins were discovered …

Prenylated indole derivatives from fungi: structure diversity, biological activities, biosynthesis and chemoenzymatic synthesis

SM Li - Natural product reports, 2010 - pubs.rsc.org
Covering: up to mid-2009 Prenylated indole alkaloids are hybrid natural products derived
from prenyl diphosphates and tryptophan or its precursors and widely distributed in …

Biosynthetic pathways to nonproteinogenic α-amino acids

JB Hedges, KS Ryan - Chemical Reviews, 2019 - ACS Publications
Natural nonproteinogenic amino acids vastly outnumber the well-known 22 proteinogenic
amino acids. Such amino acids are generated in specialized metabolic pathways. In these …

Advances in Aspergillus secondary metabolite research in the post-genomic era

JF Sanchez, AD Somoza, NP Keller… - Natural product reports, 2012 - pubs.rsc.org
Covering: 2005 to 2011 This review studies the impact of whole genome sequencing on
Aspergillus secondary metabolite research. There has been a proliferation of many new …

Host-mycobiome metabolic interactions in health and disease

N Begum, A Harzandi, S Lee, M Uhlen, DL Moyes… - Gut …, 2022 - Taylor & Francis
Fungal communities (mycobiome) have an important role in sustaining the resilience of
complex microbial communities and maintenance of homeostasis. The mycobiome remains …

Ergot alkaloids: structure diversity, biosynthetic gene clusters and functional proof of biosynthetic genes

C Wallwey, SM Li - Natural product reports, 2011 - pubs.rsc.org
Covering: 2000 to 2010 Ergot alkaloids are toxins and important pharmaceuticals which are
produced biotechnologically on an industrial scale. They have been identified in two orders …

Biosynthesis of terpenoid natural products in fungi

C Schmidt-Dannert - Biotechnology of isoprenoids, 2015 - Springer
<? xm-replace_text {Heading}?> Abstract Tens of thousands of terpenoid natural products
have been isolated from plants and microbial sources. Higher fungi (Ascomycota and …

Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase

JS Bloch, A John, R Mao, S Mukherjee… - Nature chemical …, 2023 - nature.com
C-linked glycosylation is essential for the trafficking, folding and function of secretory and
transmembrane proteins involved in cellular communication processes. The tryptophan C …