Free radicals generated due to exposure of radiation, environmental pollutants and as by-
products of metabolised drugs. These free radicals are antagonized by molecules which are …

The amide functional group plays a key role in the composition of biomolecules, including
many clinically approved drugs. Bioisosterism is widely employed in the rational …

Coumarin heterocyclic derivatives: chemical synthesis and biological activity - Natural Product
Reports (RSC Publishing) DOI:10.1039/C4NP00162A Royal Society of Chemistry View PDF …

Coumarin compounds represent an important type of naturally occurring and synthetic
oxygen-containing heterocycles with typical benzopyrone framework. This type of special …

Coumarins and flavonoids are heterocyclic molecules that have been associated with
beneficial effects on human health, such as reducing the risk of cancer, diabetes …

Coumarins, a well-known class of naturally occurring compounds, display a remarkable
array of biochemical and pharmacological actions, some of which suggest that certain …

Naturally occurring coumarins, having wide spectrum of activities such as antioxidant, anti-
inflammatory, anticancer, MAO-B inhibitory and antimicrobial, are frequently used by the …

Numerous research reports have indicated the coumarin nucleus as a potential candidate
for development of anti-inflammatory drugs. Various phytoconstituents such as …

The synthesis of coumarins through Knoevenagel condensation is one of the most important
processes in synthetic organic chemistry and medicinal chemistry. Compounds including a …

A series of coumarin–chalcone hybrids have been synthesized and evaluated for their in
vitro cytotoxicity against a panel of four human cancer cell lines and normal fibroblasts …