The evolution of gene expression in cis and trans

SA Signor, SV Nuzhdin - Trends in Genetics, 2018 - cell.com
There is abundant variation in gene expression between individuals, populations, and
species. The evolution of gene regulation and expression within and between species is …

The rise of genomics in snake venom research: recent advances and future perspectives

W Rao, K Kalogeropoulos, ME Allentoft… - …, 2022 - academic.oup.com
Snake venoms represent a danger to human health, but also a gold mine of bioactive
proteins that can be harnessed for drug discovery purposes. The evolution of snakes and …

Micro and macroevolution of sea anemone venom phenotype

EG Smith, JM Surm, J Macrander, A Simhi… - Nature …, 2023 - nature.com
Venom is a complex trait with substantial inter-and intraspecific variability resulting from
strong selective pressures acting on the expression of many toxic proteins. However …

The Tiger Rattlesnake genome reveals a complex genotype underlying a simple venom phenotype

MJ Margres, RM Rautsaw… - Proceedings of the …, 2021 - National Acad Sciences
Variation in gene regulation is ubiquitous, yet identifying the mechanisms producing such
variation, especially for complex traits, is challenging. Snake venoms provide a model …

Integrated Venomics and Venom Gland Transcriptome Analysis of Juvenile and Adult Mexican Rattlesnakes Crotalus simus, C. tzabcan, and C. culminatus …

J Durban, L Sanz, D Trevisan-Silva… - Journal of Proteome …, 2017 - ACS Publications
Adult rattlesnakes within genus Crotalus express one of two distinct venom phenotypes, type
I (hemorrhagic) and type II (neurotoxic). In Costa Rican Central American rattlesnake …

The medical threat of mamba envenoming in sub-Saharan Africa revealed by genus-wide analysis of venom composition, toxicity and antivenomics profiling of …

S Ainsworth, D Petras, M Engmark, RD Süssmuth… - Journal of …, 2018 - Elsevier
Mambas (genus Dendroaspis) are among the most feared of the medically important elapid
snakes found in sub-Saharan Africa, but many facets of their biology, including the diversity …

Molecular mechanisms underlying intraspecific variation in snake venom

DR Amazonas, JA Portes-Junior, MY Nishiyama-Jr… - Journal of …, 2018 - Elsevier
Elucidating the molecular mechanisms underlying snake venom variability provides
important clues for understanding how the biological functions of this powerful toxic arsenal …

RNA-seq analyses of the midgut from blood- and serum-fed Ixodes ricinus ticks

J Perner, J Provazník, J Schrenková, V Urbanová… - Scientific reports, 2016 - nature.com
Adult females of the genus Ixodes imbibe blood meals exceeding about 100 times their own
weight within 7‒9 days. During this period, ticks internalise components of host blood by …

Coralsnake venomics: analyses of venom gland transcriptomes and proteomes of six Brazilian taxa

SD Aird, NJ da Silva Jr, L Qiu, A Villar-Briones… - Toxins, 2017 - mdpi.com
Venom gland transcriptomes and proteomes of six Micrurus taxa (M. corallinus, M.
lemniscatus carvalhoi, M. lemniscatus lemniscatus, M. paraensis, M. spixii spixii, and M …

Snake venom gene expression is coordinated by novel regulatory architecture and the integration of multiple co-opted vertebrate pathways

BW Perry, SS Gopalan, GIM Pasquesi… - Genome …, 2022 - genome.cshlp.org
Understanding how regulatory mechanisms evolve is critical for understanding the
processes that give rise to novel phenotypes. Snake venom systems represent a valuable …