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Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …
Hydrogel‐based 3D bioprinting for bone and cartilage tissue engineering
As a milestone in soft and hard tissue engineering, a precise control over the micropatterns
of scaffolds has lightened new opportunities for the recapitulation of native body organs …
of scaffolds has lightened new opportunities for the recapitulation of native body organs …
Degradable natural polymer hydrogels for articular cartilage tissue engineering
Articular cartilage has poor ability to heal once damaged. Tissue engineering with scaffolds
of polymer hydrogels is promising for cartilage regeneration and repair. Polymer hydrogels …
of polymer hydrogels is promising for cartilage regeneration and repair. Polymer hydrogels …
The mechanobiology of articular cartilage: bearing the burden of osteoarthritis
Articular cartilage injuries and degenerative joint diseases are responsible for progressive
pain and disability in millions of people worldwide, yet there is currently no treatment …
pain and disability in millions of people worldwide, yet there is currently no treatment …
Hydrogels for the repair of articular cartilage defects
The repair of articular cartilage defects remains a significant challenge in orthopedic
medicine. Hydrogels, three-dimensional polymer networks swollen in water, offer a unique …
medicine. Hydrogels, three-dimensional polymer networks swollen in water, offer a unique …
Engineering cartilage tissue
Cartilage tissue engineering is emerging as a technique for the regeneration of cartilage
tissue damaged due to disease or trauma. Since cartilage lacks regenerative capabilities, it …
tissue damaged due to disease or trauma. Since cartilage lacks regenerative capabilities, it …
Biopolymer-based hydrogels for cartilage tissue engineering
Replacement of body parts has been studied for at least 2500 years, when missing teeth
were substituted with artificial teeth engraved from the bones of oxen. 1 Artificial substitutes …
were substituted with artificial teeth engraved from the bones of oxen. 1 Artificial substitutes …
A three-dimensional nanofibrous scaffold for cartilage tissue engineering using human mesenchymal stem cells
The utilization of adult stem cells in tissue engineering is a promising solution to the problem
of tissue or organ shortage. Adult bone marrow derived mesenchymal stem cells (MSCs) are …
of tissue or organ shortage. Adult bone marrow derived mesenchymal stem cells (MSCs) are …
Tissue engineering of functional articular cartilage: the current status
Osteoarthritis is a degenerative joint disease characterized by pain and disability. It involves
all ages and 70% of people aged> 65 have some degree of osteoarthritis. Natural cartilage …
all ages and 70% of people aged> 65 have some degree of osteoarthritis. Natural cartilage …
An introductory review of cell mechanobiology
Mechanical loads induce changes in the structure, composition, and function of living
tissues. Cells in tissues are responsible for these changes, which cause physiological or …
tissues. Cells in tissues are responsible for these changes, which cause physiological or …