The enhancement of immune responses upon treatment with immune checkpoint inhibitors
can have the desired outcome of reinvigorating antitumour immune surveillance, but often at …

Although initially described as an anti-tumor mediator, tumor necrosis factor-alpha (TNF) is
generally considered as the master pro-inflammatory cytokine. It plays a crucial role in the …

Tumour necrosis factor (TNF) is a major pro‐inflammatory cytokine involved in multiple
inflammatory diseases. The detrimental activity of TNF can be blocked by various …

There are many studies devoted to the role of hair follicle stem cells in wound healing as
well as in follicle self-restoration. At the same time, the influence of the inflammatory cells on …

An interesting puzzle is the fact that an infection of a tumor necrosis factor α (TNF)-deficient
host with pathogens such as bacteria or parasites that reside intracellularly inevitably ends …

TNFR1 is a crucial regulator of NF-ĸB-mediated proinflammatory cell survival responses and
programmed cell death (PCD). Deregulation of TNFα-and TNFR1-controlled NF-ĸB …

For the treatment of inflammatory illnesses such as rheumatoid arthritis and carditis, as well
as cancer, several anti-inflammatory medications have been created over the years to lower …

Objective To generate doxycycline‐inducible human tumor necrosis factor α (TNFα)–
transgenic mice to overcome a major disadvantage of existing transgenic mice with …

The confirmation of developmental differences between tissue macrophages and peripheral
monocytes has changed our view of the functions and dynamics of these two important …

Gut inflammation occurring in patients with inflammatory bowel diseases (IBD) is associated
with an excessive immune response that is directed against constituents of the normal …