G protein-coupled, seven-transmembrane segment receptors (GPCRs or 7TM receptors),
with more than 1000 different members, comprise the largest superfamily of proteins in the …

▪ Abstract Retinylidene proteins, containing seven membrane-embedded α-helices that form
an internal pocket in which the chromophore retinal is bound, are ubiquitous in …

Molluscs comprise the second largest phylum of animals (after arthropods), occurring in
virtually all habitats. Some are commercially important, a few are pests and some carry …

A model for the alpha-carbon positions in the seven transmembrane helices in the
rhodopsin family of G-protein-coupled receptors is presented. The model incorporates …

The G-protein coupled receptors form a large and diverse multi-gene superfamily with many
important physiological functions. As such, they have become important targets in …

The first member and eponym of the rhodopsin family was identified in the 1930s as the
visual pigment of the rod photoreceptor cell in the animal retina. It was found to be a …

The higher-order structure of G protein-coupled receptors (GPCRs) in membranes may
involve dimerization and formation of even larger oligomeric complexes. Here, we have …

Rhodopsin is the classical light sensor. Although rhodopsin has long been known to be
important for image formation in the eye, the requirements for opsins in non–image …

Cephalopods are set apart from other mollusks by their advanced behavioral abilities and
the complexity of their nervous systems. Because of the great evolutionary distance that …

Cephalopod mollusks are renowned for their colorful and dynamic body patterns, produced
by an assemblage of skin components that interact with light. These may include …