Kinesins are enzymes that use the energy of ATP to perform mechanical work. There are
approximately 14 families of kinesins within the kinesin superfamily. Family classification is …

▪ Abstract Spindle microtubules interact with mitotic chromosomes, binding to their
kinetochores to generate forces that are important for accurate chromosome segregation …

Monastrol, a cell-permeable small molecule inhibitor of the mitotic kinesin, Eg5, arrests cells
in mitosis with monoastral spindles. Here, we use monastrol to probe mitotic mechanisms …

During cell division, microtubules are arranged in a large bipolar structure, the mitotic
spindle, to segregate the duplicated chromosomes. Antiparallel microtubule overlaps in the …

The budding yeast protein Kip3p is a member of the conserved kinesin-8 family of
microtubule motors, which are required for microtubule–cortical interactions, normal spindle …

Although the microtubule-depolymerizing KinI motor Kif2a is abundantly expressed in
neuronal cells, we now show it localizes to centrosomes and spindle poles during mitosis in …

CLIPs are microtubule plus end-associated proteins that mediate interactions required for
cell polarity and cell division. Here we demonstrate that budding yeast Bik1, unlike its …

Ctf8p is a component of Ctf18-RFC, an alternative replication factor C-like complex required
for efficient sister chromatid cohesion in Saccharomyces cerevisiae. We performed synthetic …

Mitosis is the process by which eukaryotic cells organize and segregate their chromosomes
in preparation for cell division. It is accomplished by a cellular machine composed largely of …

It is undeniable that English has established itself as a language of international prestige,
given its status of lingua franca in many important fields of contemporary life (Hoffman 2000) …