Biomarkers of stroke recovery: consensus-based core recommendations from the stroke recovery and rehabilitation roundtable

LA Boyd, KS Hayward, NS Ward… - … Journal of Stroke, 2017 - journals.sagepub.com
The most difficult clinical questions in stroke rehabilitation are “What is this patient's potential
for recovery?” and “What is the best rehabilitation strategy for this person, given her/his …

What are white matter hyperintensities made of? Relevance to vascular cognitive impairment

JM Wardlaw, MC Valdés Hernández… - Journal of the …, 2015 - ahajournals.org
White matter hyperintensities (WMH) of presumed vascular origin, also referred to as
leukoaraiosis, are a very common finding on brain magnetic resonance imaging (MRI) or …

Clinical significance of magnetic resonance imaging markers of vascular brain injury: a systematic review and meta-analysis

S Debette, S Schilling, MG Duperron… - JAMA …, 2019 - jamanetwork.com
Importance Covert vascular brain injury (VBI) is highly prevalent in community-dwelling
older persons, but its clinical and therapeutic implications are debated. Objective To better …

[HTML][HTML] Diffusion tensor imaging of the brain

AL Alexander, JE Lee, M Lazar, AS Field - Neurotherapeutics, 2007 - Elsevier
Diffusion tensor imaging (DTI) is a promising method for characterizing microstructural
changes or differences with neuropathology and treatment. The diffusion tensor may be …

Clinical, imaging, and pathological heterogeneity of the Alzheimer's disease syndrome

B Lam, M Masellis, M Freedman, DT Stuss… - Alzheimer's research & …, 2013 - Springer
With increasing knowledge of clinical in vivo biomarkers and the pathological intricacies of
Alzheimer's disease (AD), nosology is evolving. Harmonized consensus criteria that …

Structural imaging measures of brain aging

SN Lockhart, C DeCarli - Neuropsychology review, 2014 - Springer
During the course of normal aging, biological changes occur in the brain that are associated
with changes in cognitive ability. This review presents data from neuroimaging studies of …

Heterogeneity in age-related white matter changes

R Schmidt, H Schmidt, J Haybaeck, M Loitfelder… - Acta …, 2011 - Springer
White matter changes occur endemically in routine magnetic resonance imaging (MRI)
scans of elderly persons. MRI appearance and histopathological correlates of white matter …

Cognitive aging, executive function, and fractional anisotropy: a diffusion tensor MR imaging study

SM Grieve, LM Williams, RH Paul, CR Clark… - American Journal of …, 2007 - ajnr.org
BACKGROUND AND PURPOSE: Fractional anisotropy (FA) is a useful measure of
connectivity in the brain that can be derived from the diffusion tensor imaging (DTI) dataset …

Vascular cognitive impairment: current concepts and clinical developments

P Moorhouse, K Rockwood - The Lancet Neurology, 2008 - thelancet.com
Vascular cognitive impairment (VCI) comprises a range of cognitive disorders related to
cerebral vessel disease and has generally replaced the term multi-infarct dementia. Despite …

[HTML][HTML] White matter integrity in small vessel disease is related to cognition

AM Tuladhar, AGW van Norden, KF de Laat… - NeuroImage: Clinical, 2015 - Elsevier
Cerebral small vessel disease, including white matter hyperintensities (WMH) and lacunes
of presumed vascular origin, is common in elderly people and is related to cognitive …