Mechanical and biological effects of ultrasound: a review of present knowledge

Z Izadifar, P Babyn, D Chapman - Ultrasound in medicine & biology, 2017 - Elsevier
Ultrasound is widely used for medical diagnosis and increasingly for therapeutic purposes.
An understanding of the bio-effects of sonography is important for clinicians and scientists …

Mechanical bioeffects of ultrasound

D Dalecki - Annu. Rev. Biomed. Eng., 2004 - annualreviews.org
▪ Abstract Ultrasound is used widely in medicine as both a diagnostic and therapeutic tool.
Through both thermal and nonthermal mechanisms, ultrasound can produce a variety of …

Noninvasive MR imaging–guided focal opening of the blood-brain barrier in rabbits

K Hynynen, N McDannold, N Vykhodtseva, FA Jolesz - Radiology, 2001 - pubs.rsna.org
PURPOSE: To determine if focused ultrasound beams can be used to locally open the blood-
brain barrier without damage to surrounding brain tissue and if magnetic resonance (MR) …

Delivery of colloidal particles and red blood cells to tissue through microvessel ruptures created by targeted microbubble destruction with ultrasound

RJ Price, DM Skyba, S Kaul, TC Skalak - Circulation, 1998 - ahajournals.org
Background—We have previously shown that the application of ultrasound to thin-shelled
microbubbles flowing through small microvessels (< 7 μm in diameter) produces vessel wall …

Targeted delivery of gas-filled microspheres, contrast agents for ultrasound imaging

AL Klibanov - Advanced drug delivery reviews, 1999 - Elsevier
Gas-filled microbubbles, with the size of several micrometres, are strong scatterers of
ultrasound waves used in diagnostic imaging. Application of these microbubbles as …

Vascular effects induced by combined 1-MHz ultrasound and microbubble contrast agent treatments in vivo

JH Hwang, AA Brayman, MA Reidy, TJ Matula… - Ultrasound in medicine …, 2005 - Elsevier
Previous in vivo studies have demonstrated that microvessel hemorrhages and alterations of
endothelial permeability can be produced in tissues containing microbubble-based …

Diagnostic ultrasound activation of contrast agent gas bodies induces capillary rupture in mice

DL Miller, J Quddus - Proceedings of the National Academy of Sciences, 2000 - pnas.org
Interaction of diagnostic ultrasound with gas bodies produces a useful contrast effect in
medical images, but the same interaction also represents a mechanism for bioeffects …

Dynamics of bubble oscillation in constrained media and mechanisms of vessel rupture in SWL

P Zhong, Y Zhou, S Zhu - Ultrasound in medicine & biology, 2001 - Elsevier
Rupture of small blood vessels is a primary feature of the vascular injury associated with
shock-wave lithotripsy (SWL) and cavitation has been implicated as a potential mechanism …

Theranostics in the vasculature: bioeffects of ultrasound and microbubbles to induce vascular shutdown

F Padilla, J Brenner, F Prada, AL Klibanov - Theranostics, 2023 - pmc.ncbi.nlm.nih.gov
Ultrasound-triggered microbubbles destruction leading to vascular shutdown have resulted
in preclinical studies in tumor growth delay or inhibition, lesion formation, radio-sensitization …

Elastography for the pancreas: Current status and future perspective

N Kawada, S Tanaka - World journal of gastroenterology, 2016 - pmc.ncbi.nlm.nih.gov
Elastography for the pancreas can be performed by either ultrasound or endoscopic
ultrasound (EUS). There are two types of pancreatic elastographies based on different …