An update on regulation and function of G protein-coupled receptors in cancer: A promising strategy for cancer therapy

L Li, Z An, C Lin, Q Xu, C Tang - … et Biophysica Acta (BBA)-Reviews on …, 2025 - Elsevier
G protein-coupled receptors (GPCRs) are a large family of cell surface receptors that play a
crucial role in signal transduction and cellular communication. GPCR proteins are involved …

[HTML][HTML] Long Non-Coding RNAs in Ovarian Cancer: Mechanistic Insights and Clinical Applications

S Basu, R Nadhan, DN Dhanasekaran - Cancers, 2025 - mdpi.com
Abstract Background/Objectives: Ovarian cancer is a leading cause of gynecological cancer
mortality worldwide, often diagnosed at advanced stages due to vague symptoms and the …

5-Aminoimidazole-4-carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase promotes pulmonary arterial smooth muscle cell …

X Shi, Q Ma, Y Huo, Y Su - American Journal of Physiology …, 2024 - journals.physiology.org
Pulmonary arterial hypertension (PAH) is a debilitating vascular disorder characterized by
abnormal pulmonary artery smooth muscle cell (PASMC) proliferation and collagen …

Tumor-infiltrating B cell-related lncRNA crosstalk reveals clinical outcomes and tumor immune microenvironment in ovarian cancer based on single-cell and bulk RNA …

Y Huang, Z Gui, M Wu, M Zhang, Y Jiang, Q Ding… - Heliyon, 2024 - cell.com
Background The tumor immune microenvironment (TIME) plays a pivotal role in determining
ovarian cancer (OC) prognosis. Long non-coding RNAs (lncRNAs) are key regulators of …

[HTML][HTML] Optimizing lncRNA-miRNA interaction analysis: Modified crosslinking and immunoprecipitation (M-CLIP) assay

R Nadhan, R Gomathinayagam, R Radhakrishnan… - MethodsX, 2024 - Elsevier
Defining lncRNA-miRNA interactions is critical for understanding their roles in cellular
signaling and cancer biology. Capturing these interactions is challenging due to the inherent …

[PDF][PDF] LncRNAs in Ovarian Cancer: Mechanistic Insights and Clinical Applications

S Basu, R Nadhan, DN Dhanasekaran - 2024 - preprints.org
Background/Objectives: Ovarian cancer is a leading cause of gynecological cancer mortality
worldwide, often diagnosed at advanced stages due to vague symptoms and lack of …

siRNA 药物在肿瘤靶向治疗中的研究进展

张从一, 牧原, **振海, 王欣月, 蔡文秋, 刘晓婧, 邹倩… - 药学进展, 2024 - pps.cpu.edu.cn
小干扰RNA (siRNA) 是一种新型核酸药物, 其通过RNA 干扰(RNAi) 机制,
在转录后水**靶向沉默靶基因的表达, 从而发挥治疗疾病的作用. siRNA 作为一种精准, 特异 …

Utilizing Machine Learning to Identify an Icd Signature to Enhance Outcomes in Individuals Diagnosed with Ovarian Cancer

T Gao, P Zhao, X Sun, H Chen - papers.ssrn.com
Background: Ovarian cancer (OV) is a prevalent cancer that has a high fatality rate among
females. The lack of a reliable predictive biomarker undermines the efficiency of anticipation …