Interactions between Borrelia burgdorferi and ticks

C Kurokawa, GE Lynn, JHF Pedra, U Pal… - Nature Reviews …, 2020 - nature.com
Borrelia burgdorferi is the causative agent of Lyme disease and is transmitted to vertebrate
hosts by Ixodes spp. ticks. The spirochaete relies heavily on its arthropod host for basic …

The essential role of tick salivary glands and saliva in tick feeding and pathogen transmission

L Šimo, M Kazimirova, J Richardson… - Frontiers in cellular and …, 2017 - frontiersin.org
As long-term pool feeders, ticks have developed myriad strategies to remain discreetly but
solidly attached to their hosts for the duration of their blood meal. The critical biological …

Tick salivary compounds: their role in modulation of host defences and pathogen transmission

M Kazimírová, I Štibrániová - Frontiers in cellular and infection …, 2013 - frontiersin.org
Ticks require blood meal to complete development and reproduction. Multifunctional tick
salivary glands play a pivotal role in tick feeding and transmission of pathogens. Tick …

Insect natural products and processes: new treatments for human disease

NA Ratcliffe, CB Mello, ES Garcia, TM Butt… - Insect biochemistry and …, 2011 - Elsevier
In this overview, some of the more significant recent developments in bioengineering natural
products from insects with use or potential use in modern medicine are described, as well as …

Tick-borne viruses and biological processes at the tick-host-virus interface

M Kazimírová, S Thangamani, P Bartíková… - Frontiers in cellular …, 2017 - frontiersin.org
Ticks are efficient vectors of arboviruses, although less than 10% of tick species are known
to be virus vectors. Most tick-borne viruses (TBV) are RNA viruses some of which cause …

Wonders of tick saliva

PA Nuttall - Ticks and tick-borne diseases, 2019 - Elsevier
Saliva of ticks is arguably the most complex saliva of any animal. This is particularly the case
for ixodid species that feed for many days firmly attached to the same skin site of their …

Tick host immunity: vector immunomodulation and acquired tick resistance

C Kitsou, E Fikrig, U Pal - Trends in immunology, 2021 - cell.com
Ticks have an unparalleled ability to parasitize diverse land vertebrates. Their natural
persistence and vector competence are supported by the evolution of sophisticated …

Discovery of exosomes from tick saliva and salivary glands reveals therapeutic roles for CXCL12 and IL-8 in wound healing at the tick–human skin interface

W Zhou, F Tahir, JCY Wang, M Woodson… - Frontiers in cell and …, 2020 - frontiersin.org
Ticks secrete various anti-coagulatory, anti-vasoconstrictory, anti-inflammatory, and anti-
platelet aggregation factors in their saliva at the bite site during feeding to evade host …

Ticks and their epidemiological role in Slovakia: From the past till present

M Stanko, M Derdáková, E Špitalská, M Kazimírová - Biologia, 2022 - Springer
In Slovakia, 22 tick species have been found to occur to date. Among them, Ixodes ricinus,
Dermacentor reticulatus, D. marginatus and marginally Haemaphysalis concinna, H. inermis …

Changing the recipe: Pathogen directed changes in tick saliva components

M Pham, J Underwood, AS Oliva Chávez - International journal of …, 2021 - mdpi.com
Ticks are obligate hematophagous parasites and are important vectors of a wide variety of
pathogens. These pathogens include spirochetes in the genus Borrelia that cause Lyme …