The population of cancer survivors is rapidly increasing due to improving healthcare.
However, cancer therapies often have long-term side effects. One example is cancer therapy …

Background and Purpose: Natriuretic peptides have led the way as a diagnostic and
prognostic tool for the diagnosis and management of heart failure (HF). More recent …

Develo** a single-domain assay to identify individuals at high risk of future events is a
priority for multi-disease and mortality prevention. By training a neural network, we …

New biomarkers are being evaluated for their ability to advance the management of patients
with heart failure. Despite a large pool of interesting candidate biomarkers, besides …

BACKGROUND Growth differentiation factor 15 (GDF-15) is expressed and secreted in
response to inflammation, oxidative stress, hypoxia, telomere erosion, and oncogene …

According to the Geroscience concept that organismal aging and age-associated diseases
share the same basic molecular mechanisms, the identification of biomarkers of age that can …

Background The extent to which co-occurrence of cardiovascular disease (CVD) and cancer
is due to shared risk factors or other mechanisms is unknown. Objectives This study …

Diabetes is one of the leading causes of kidney disease. Diabetic kidney disease (DKD) is a
major cause of end-stage kidney disease (ESKD) worldwide, and it is linked to an increase …

GDF15 has recently gained scientific and translational prominence with the discovery that its
receptor is a GFRAL-RET heterodimer of which GFRAL is expressed solely in the hindbrain …

Growth and differentiation factor 15 (GDF15) belongs to the transforming growth factor-β
(TGF-β) superfamily of proteins. Glial-derived neurotrophic factor (GDNF) family receptor α …