Neural recording electrode technologies have contributed considerably to neuroscience by
enabling the extracellular detection of low-frequency local field potential oscillations and …

A major shift is happening within neurophysiology: a population doctrine is drawing level
with the single-neuron doctrine that has long dominated the field. Population-level ideas …

Spike sorting is the computational process of extracting the firing times of single neurons
from recordings of local electrical fields. This is an important but hard problem in …

The accumulation of metabolic waste is a leading cause of numerous neurological
disorders, yet we still have only limited knowledge of how the brain performs self-cleansing …

INTRODUCTION Electrode arrays based on complementary metal-oxide semiconductor
silicon fabrication technology, such as Neuropixels probes, have enabled recordings of …

Spike sorting is the computational process of extracting the firing times of single neurons
from recordings of local electrical fields. This is an important but hard problem in …

Vision, choice, action and behavioural engagement arise from neuronal activity that may be
distributed across brain regions. Here we delineate the spatial distribution of neurons …

The transmission of the heartbeat through the cerebral vascular system causes intracranial
pressure pulsations. We discovered that arterial pressure pulsations can directly modulate …

Throughout development, the brain transits from early highly synchronous activity patterns to
a mature state with sparse and decorrelated neural activity, yet the mechanisms underlying …

Brain organoids are important models for mimicking some three-dimensional (3D)
cytoarchitectural and functional aspects of the brain. Multielectrode arrays (MEAs) that …