Valvular heart disease is a major cause of morbidity and mortality worldwide. Surgical valve
repair or replacement has been the standard of care for patients with valvular heart disease …

Precision medicine is a new frontier in healthcare that uses scientific methods to customize
medical treatment to the individual genes, anatomy, physiology, and lifestyle of each person …

Valvular heart disease is an important source of cardiovascular morbidity and mortality.
Current prosthetic valve replacement options, such as bioprosthetic and mechanical heart …

Background The postoperative outcomes of transcatheter aortic valve replacement (TAVR)
with the new generation of self-expanding valves (SEV) and balloon-expandable valves …

The native human heart valve leaflet contains a layered microstructure comprising a
hierarchical arrangement of collagen, elastin, proteoglycans and various cell types. Here …

Transcatheter aortic valve replacement (TAVR) is a minimally invasive procedure that
provides an effective alternative to open-heart surgical valve replacement for treating …

Indications for transcatheter aortic valve replacement (TAVR) have steadily increased over
the last decade since the first trials including inoperable or very high risk patients. Thus …

Nearly a century after rheumatic fever (RF) and rheumatic heart disease (RHD) was
eradicated from the developed world, the disease remains endemic in many low-and middle …

The durability of the current polymeric heart valves remains to be improved, which has
proven to be highly dynamics and species dependent. Herein, inspired by the fiber …

Aortic stenosis (AS) is the most prevalent heart valve disease in western countries that
poses a significant public health challenge due to the lack of a medical treatment to prevent …