Estrogen receptor signaling mechanisms

N Fuentes, P Silveyra - Advances in protein chemistry and structural …, 2019 - Elsevier
The primary female sex hormones, estrogens, are responsible for the control of functions of
the female reproductive system, as well as the development of secondary sexual …

Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics

P Huang, V Chandra… - Annual review of …, 2010 - annualreviews.org
As ligand-regulated transcription factors, the nuclear hormone receptors are nearly ideal
drug targets, with internal pockets that bind to hydrophobic, drug-like molecules and well …

[KSIĄŻKA][B] Principles and practice of phytotherapy: modern herbal medicine

K Bone, S Mills - 2012 - books.google.com
The authoritative and comprehensive modern textbook on western herbal medicine-now in
its second edition This long-awaited second edition of Principles and Practice of …

Estrogens and phytoestrogens in body functions

I Ceccarelli, L Bioletti, S Peparini, E Solomita… - Neuroscience & …, 2022 - Elsevier
Estrogens are the hormones of reproduction in women as well as of many other important
functions in the male and female body. They undergo significant changes in the different …

[HTML][HTML] Phytoestrogens and breast cancer: In vitro anticancer activities of isoflavones, lignans, coumestans, stilbenes and their analogs and derivatives

P Basu, C Maier - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Breast cancer is one of the leading causes of cancer-related morbidity and mortality among
women worldwide. Phytoestrogens, plant-derived polyphenols that structurally and …

The role of isoflavones in the prevention of breast cancer and prostate cancer

T Pejčić, M Zeković, U Bumbaširević, M Kalaba, I Vovk… - Antioxidants, 2023 - mdpi.com
This narrative review summarizes epidemiological studies on breast cancer and prostate
cancer with an overview of their global incidence distribution to investigate the relationship …

Considerations for the use of polyphenols as therapies in neurodegenerative diseases

J Renaud, MG Martinoli - International Journal of Molecular Sciences, 2019 - mdpi.com
Over the last two decades, the increase in the incidence of neurodegenerative diseases due
to the increasingly ageing population has resulted in a major social and economic burden …

Estrogen and glycemic homeostasis: the fundamental role of nuclear estrogen receptors ESR1/ESR2 in glucose transporter GLUT4 regulation

KCR Gregorio, CP Laurindo, UF Machado - Cells, 2021 - mdpi.com
Impaired circulating estrogen levels have been related to impaired glycemic homeostasis
and diabetes mellitus (DM), both in females and males. However, for the last twenty years …

The anti-inflammatory activities of Tanshinone IIA, an active component of TCM, are mediated by estrogen receptor activation and inhibition of iNOS

GW Fan, XM Gao, H Wang, Y Zhu, J Zhang… - The Journal of steroid …, 2009 - Elsevier
Tanshinone IIA (Tan IIA) is a major compound extracted from a traditional herbal medicine
Salvia miltiorrhiza BUNGE, which is used to treat cardiovascular diseases, cerebrovascular …

Mechanisms underlying the dualistic mode of action of major soy isoflavones in relation to cell proliferation and cancer risks

IMCM Rietjens, AM Sotoca, J Vervoort… - Molecular nutrition & …, 2013 - Wiley Online Library
Isoflavones are phytoestrogens that have been linked to both beneficial as well as adverse
effects in relation to cell proliferation and cancer risks. The present article presents an …