All life forms have evolved under the constant force of gravity on Earth and developed ways
to counterbalance acceleration load. In space, shear forces, buoyance-driven convection …

Functioning as the outermost self-renewing protective layer of the human organism, skin
protects against a multitude of harmful biological and physical stimuli. Consisting of …

Spaceflight-associated immune system weakening ultimately limits the ability of humans to
expand their presence beyond the earth's orbit. A mechanistic study of microgravity …

We have identified and validated a spaceflight-associated microRNA (miRNA) signature that
is shared by rodents and humans in response to simulated, short-duration and long-duration …

Novel, non-invasive biomarkers to diagnose breast cancer with high sensitivity and
specificity are greatly desired. Circulating microRNAs (miRNAs) show potential for breast …

Gravity constituted the only constant environmental parameter, during the evolutionary
period of living matter on Earth. However, whether gravity has affected the evolution of …

One of the greatest challenges of humanity for deep space exploration is to fully understand
how altered gravitational conditions affect human physiology. It is evident that the spaceflight …

In the era of renewed space exploration, comprehending the effects of the space
environment on human health, particularly for deep space missions, is crucial. While …

Translating fundamental biological discoveries from NASA Space Biology program into
health risk from space flights has been an ongoing challenge. We propose to use NASA …

The immune systems can be altered by spaceflight in many aspects, but microgravity‐
related mucosal immune changes and its clinical significance have not been well studied …