Is frailty associated with adverse outcomes after orthopaedic surgery?: a systematic review and assessment of definitions

JL Lemos, JM Welch, M **ao, LM Shapiro, E Adeli… - JBJS …, 2021 - journals.lww.com
Background: There is increasing evidence supporting the association between frailty and
adverse outcomes after surgery. There is, however, no consensus on how frailty should be …

Frailty in patients undergoing surgery for brain tumors: a systematic review of the literature

S Huq, J Liu, R Romano, S Seal, AM Khalafallah… - World neurosurgery, 2022 - Elsevier
Background Emerging literature suggests that frailty may be an important driver of
postoperative outcomes in patients undergoing surgery for brain tumors. We systematically …

Frailty status is a more robust predictor than age of spinal tumor surgery outcomes: a NSQIP analysis of 4,662 patients

SF Kazim, AJ Dicpinigaitis, CA Bowers, S Shah… - …, 2022 - pmc.ncbi.nlm.nih.gov
Objective The present study aimed to evaluate the effect of baseline frailty status (as
measured by modified frailty index-5 [mFI-5]) versus age on postoperative outcomes of …

Implication of nutritional status for adverse outcomes after surgery for metastatic spine tumors

GH Rigney, E Massaad, A Kiapour, SS Razak… - … of Neurosurgery: Spine, 2023 - thejns.org
OBJECTIVE Surgery for metastatic spinal tumors can have a substantial impact on patients'
quality of life by alleviating pain, improving function, and correcting spinal instability when …

Frailty and outcomes after craniotomy for brain tumor

RA Sastry, NJ Pertsch, O Tang, B Shao… - Journal of Clinical …, 2020 - Elsevier
Frailty has been associated with increased morbidity and mortality in a variety of surgical
disciplines. Few data exist regarding the relationship of frailty with adverse outcomes in …

Frailty predicts worse outcomes after intracranial meningioma surgery irrespective of existing prognostic factors

BC Theriault, J Pazniokas, AS Adkoli, EK Cho… - Neurosurgical …, 2020 - thejns.org
OBJECTIVE Frailty has been recognized as a predictor of adverse surgical outcomes across
multiple surgical disciplines, but until now the relationship between frailty and intracranial …

Evaluating frailty, mortality, and complications associated with metastatic spine tumor surgery using machine learning–derived body composition analysis

E Massaad, CP Bridge, A Kiapour… - … of Neurosurgery: Spine, 2022 - thejns.org
OBJECTIVE Cancer patients with spinal metastases may undergo surgery without clear
assessments of prognosis, thereby impacting the optimal palliative strategy. Because the …

Performance assessment of the metastatic spinal tumor frailty index using machine learning algorithms: limitations and future directions

E Massaad, N Williams, M Hadzipasic, SS Patel… - Neurosurgical …, 2021 - thejns.org
OBJECTIVE Frailty is recognized as an important consideration in patients with cancer who
are undergoing therapies, including spine surgery. The definition of frailty in the context of …

Newly diagnosed glioblastoma in geriatric (65+) patients: impact of patients frailty, comorbidity burden and obesity on overall survival

M Schneider, AL Potthoff, E Scharnböck… - Journal of neuro …, 2020 - Springer
Object Increasing age is a known negative prognostic factor for glioblastoma. However, a
multifactorial approach is necessary to achieve optimal neuro-oncological treatment. It …

Association of baseline frailty status and age with outcomes in patients undergoing intracranial meningioma surgery: results of a nationwide analysis of 5818 patients …

KL Cole, SF Kazim, R Thommen… - European Journal of …, 2022 - Elsevier
Purpose The objective of this study was to compare the effect of frailty, as measured by the 5-
factor modified frailty index (mFI-5), with that of age on postoperative outcomes of patients …