Micro total analysis systems: fundamental advances and applications in the laboratory, clinic, and field
Assay devices designed for these applications offer improvements to existing methods or
provide fundamentally new strategies. Both mature methods and novel techniques have …
provide fundamentally new strategies. Both mature methods and novel techniques have …
Microfluidics for understanding model organisms
New microfluidic systems for whole organism analysis and experimentation are catalyzing
biological breakthroughs across many fields, from human health to fundamental biology …
biological breakthroughs across many fields, from human health to fundamental biology …
Effective drug combination for Caenorhabditis elegans nematodes discovered by output-driven feedback system control technique
Infections from parasitic nematodes (or roundworms) contribute to a significant disease
burden and productivity losses for humans and livestock. The limited number of …
burden and productivity losses for humans and livestock. The limited number of …
[HTML][HTML] Caenorhabditis elegans in anthelmintic research–Old model, new perspectives
SR Hahnel, CM Dilks, I Heisler, EC Andersen… - International journal for …, 2020 - Elsevier
For more than four decades, the free-living nematode Caenorhabditis elegans has been
extensively used in anthelmintic research. Classic genetic screens and heterologous …
extensively used in anthelmintic research. Classic genetic screens and heterologous …
High-throughput imaging of neuronal activity in Caenorhabditis elegans
J Larsch, D Ventimiglia… - Proceedings of the …, 2013 - National Acad Sciences
Neuronal responses to sensory inputs can vary based on genotype, development,
experience, or stochastic factors. Existing neuronal recording techniques examine a single …
experience, or stochastic factors. Existing neuronal recording techniques examine a single …
C. elegans as a tool for in vivo nanoparticle assessment
Abstract Characterization of the in vivo behavior of nanomaterials aims to optimize their
design, to determine their biological effects, and to validate their application. The …
design, to determine their biological effects, and to validate their application. The …
Whole-organism behavioral profiling reveals a role for dopamine in state-dependent motor program coupling in C. elegans
Animal behaviors are commonly organized into long-lasting states that coordinately impact
the generation of diverse motor outputs such as feeding, locomotion, and grooming …
the generation of diverse motor outputs such as feeding, locomotion, and grooming …
Upconverting microgauges reveal intraluminal force dynamics in vivo
The forces generated by action potentials in muscle cells shuttle blood, food and waste
products throughout the luminal structures of the body. Although non-invasive …
products throughout the luminal structures of the body. Although non-invasive …
Chip technologies for screening chemical and biological agents against plant-parasitic nematodes
Plant-parasitic nematodes cause substantial damage to agricultural crops worldwide. Long-
term management of these pests requires novel strategies to reduce infection of host plants …
term management of these pests requires novel strategies to reduce infection of host plants …
A high-throughput behavioral screening platform for measuring chemotaxis by C. elegans
E Fryer, S Guha, LE Rogel-Hernandez… - Plos …, 2024 - journals.plos.org
Throughout history, humans have relied on plants as a source of medication, flavoring, and
food. Plants synthesize large chemical libraries and release many of these compounds into …
food. Plants synthesize large chemical libraries and release many of these compounds into …