We describe the isolation of mutations in dynamin-associated protein 160 kDa (dap160), the
Drosophila homolog of intersectin, a putative adaptor for proteins involved in endocytosis …

Background The recent availability of genome sequences has provided unparalleled
insights into the broad-scale patterns of transposable element (TE) sequences in eukaryotic …

Epithelial tubes are the functional units of many organs, but little is known about how tube
sizes are established. Using the Drosophila tracheal system as a model, we previously …

Next-generation sequencing is commonly used to screen for pathogenic mutations in
families with Mendelian disorders, but due to the pace of discoveries, gaps have widened for …

Hundreds of Drosophila melanogaster stocks are currently maintained at the Bloomington
Drosophila Stock Center with mutations that have not been associated with sequence …

The heterochromatin of chromosome 2 of Drosophila melanogaster has been among the
best characterized models for functional studies of heterochromatin owing to its abundance …

Drosophila mutants have played an important role in elucidating the physiologic function of
genes. Large-scale projects have succeeded in producing mutations in a large proportion of …