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The chemistry of snake venom and its medicinal potential
The fascination and fear of snakes dates back to time immemorial, with the first scientific
treatise on snakebite envenoming, the Brooklyn Medical Papyrus, dating from ancient Egypt …
treatise on snakebite envenoming, the Brooklyn Medical Papyrus, dating from ancient Egypt …
[HTML][HTML] Snake venoms in drug discovery: valuable therapeutic tools for life saving
Animal venoms are used as defense mechanisms or to immobilize and digest prey. In fact,
venoms are complex mixtures of enzymatic and non-enzymatic components with specific …
venoms are complex mixtures of enzymatic and non-enzymatic components with specific …
Lys49 myotoxins, secreted phospholipase A2-like proteins of viperid venoms: A comprehensive review
B Lomonte - Toxicon, 2023 - Elsevier
Muscle necrosis is a potential clinical complication of snakebite envenomings, which in
severe cases can lead to functional or physical sequelae such as disability or amputation …
severe cases can lead to functional or physical sequelae such as disability or amputation …
[HTML][HTML] Antimicrobials from venomous animals: An overview
The inappropriate or excessive use of antimicrobial agents caused an emerging public
health problem due to the resulting resistance developed by microbes. Therefore, there is an …
health problem due to the resulting resistance developed by microbes. Therefore, there is an …
Snake venom L‐amino acid oxidases: Trends in pharmacology and biochemistry
LFM Izidoro, JC Sobrinho, MM Mendes… - BioMed research …, 2014 - Wiley Online Library
L‐amino acid oxidases are enzymes found in several organisms, including venoms of
snakes, where they contribute to the toxicity of ophidian envenomation. Their toxicity is …
snakes, where they contribute to the toxicity of ophidian envenomation. Their toxicity is …
Neurotoxins acting at synaptic sites: A brief review on mechanisms and clinical applications
Neurotoxins generally inhibit or promote the release of neurotransmitters or bind to
receptors that are located in the pre-or post-synaptic membranes, thereby affecting …
receptors that are located in the pre-or post-synaptic membranes, thereby affecting …
Past decade study of snake venom L-amino acid oxidase
C Guo, S Liu, Y Yao, Q Zhang, MZ Sun - Toxicon, 2012 - Elsevier
As one of the major protein (enzyme) components of snake venom (SV), l-amino acid
oxidase (LAAO) plays an important role in the toxicities and biological activities for SV …
oxidase (LAAO) plays an important role in the toxicities and biological activities for SV …
Snake venom: From fieldwork to the clinic: Recent insights into snake biology, together with new technology allowing high‐throughput screening of venom, bring new …
Snake venoms are recognized here as a grossly under‐explored resource in
pharmacological prospecting. Discoveries in snake systematics demonstrate that former …
pharmacological prospecting. Discoveries in snake systematics demonstrate that former …
Development of peptide and protein nanotherapeutics by nanoencapsulation and nanobioconjugation
The targeted delivery of therapeutic peptide by nanocarriers systems requires the
knowledge of interactions of nanomaterials with the biological environment, peptide release …
knowledge of interactions of nanomaterials with the biological environment, peptide release …
Structure–function studies and mechanism of action of snake venom L-amino acid oxidases
A Ullah - Frontiers in pharmacology, 2020 - frontiersin.org
Snake venom L-amino acid oxidases (SV-LAAOs) are the least studied venom enzymes.
These enzymes catalyze the stereospecific oxidation of an L-amino acid to their …
These enzymes catalyze the stereospecific oxidation of an L-amino acid to their …