Microbiota–gut–brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities

MA Ortega, MA Álvarez-Mon, C García-Montero… - Molecular …, 2023 - nature.com
Bipolar disorders (BD) represent a severe leading disabling mental condition worldwide
characterized by episodic and often progressive mood fluctuations with manic and …

Inflammation in psychiatric disorders: what comes first?

ME Bauer, AL Teixeira - Annals of the New York Academy of …, 2019 - Wiley Online Library
Neuropsychiatric disorders (ie, mood disorders and schizophrenia) and inflammation are
closely intertwined, and possibly powering each other in a bidirectional loop. Depression …

Inflammatory mediators in major depression and bipolar disorder

S Poletti, MG Mazza, F Benedetti - Translational Psychiatry, 2024 - nature.com
Major depressive disorder (MDD) and bipolar disorder (BD) are highly disabling illnesses
defined by different psychopathological, neuroimaging, and cognitive profiles. In the last …

The HPA axis in bipolar disorder: systematic review and meta-analysis

MB Murri, D Prestia, V Mondelli, C Pariante… - …, 2016 - Elsevier
Objectives To provide a quantitative and qualitative synthesis of the available evidence on
the role of Hypothalamic–Pituitary–Adrenal (HPA) axis in the pathophysiology of Bipolar …

[HTML][HTML] Inflammation, anxiety, and stress in bipolar disorder and borderline personality disorder: A narrative review

LF Saccaro, Z Schilliger, A Dayer, N Perroud… - Neuroscience & …, 2021 - Elsevier
Bipolar disorder (BD) and borderline personality disorder (BPD) are serious and prevalent
psychiatric diseases that share common phenomenological characteristics: symptoms (such …

Neuroinflammation in mood disorders: role of regulatory immune cells

ME Bauer, AL Teixeira - Neuroimmunomodulation, 2021 - karger.com
Mood disorders are associated with chronic low-grade systemic (sterile) inflammation, with
increased plasma levels of pro-inflammatory mediators targeting all tissues including the …

Revisiting inflammation in bipolar disorder

GR Fries, C Walss-Bass, ME Bauer… - … Biochemistry and Behavior, 2019 - Elsevier
Bipolar disorder (BD) has been associated with immune changes, and yet their underlying
mechanisms are still not fully understood. Here, we review the current state of the field …

The theory of bipolar disorder as an illness of accelerated aging: implications for clinical care and research

LB Rizzo, LG Costa, RB Mansur, W Swardfager… - Neuroscience & …, 2014 - Elsevier
Bipolar Disorder (BD) has been conceptualized as both a cyclic and a progressive disorder.
Mechanisms involved in neuroprogression in BD remain largely unknown although several …

Inflammatory biomarker profiles of mental disorders and their relation to clinical, social and lifestyle factors

D Baumeister, A Russell, CM Pariante… - Social psychiatry and …, 2014 - Springer
In the last few decades, mental health research has increasingly provided evidence
supporting the role of inflammation in pathogenesis, course and treatment of mental …

The immunology of bipolar disorder

IG Barbosa, R Machado-Vieira, JC Soares… - …, 2014 - karger.com
Bipolar disorder (BD) is a psychiatric condition associated with elevated frequency of clinical
comorbidities and cognitive impairment. The neurobiology of BD is not completely …