In search of an ideal partner or alternative to conventional immunosuppressive agents,
rabbit anti-thymocyte globulin (ATG) and, more recently, post-transplant cyclophosphamide …

Acquired aplastic anemia (AA) is an immune-mediated bone marrow (BM) failure where
marrow disruption is driven by a cytotoxic T-cell–mediated autoimmune attack against …

Chronic graft-versus-host disease (cGVHD) is a serious complication of allogeneic stem cell
transplantation with few effective options available after failure of corticosteroids. B and T …

Background Previously, we demonstrated that the addition of anti-human-T-lymphocyte
immunoglobulin (ATLG) to standard ciclosporin and methotrexate prophylaxis reduced graft …

Bruton's tyrosine kinase (BTK) inhibitors have revolutionized the landscape for the treatment
of hematological malignancies, solid tumors, and, recently, autoimmune disorders. The BTK …

Background The optimal dose of rabbit antithymocyte globulin (ATG, ImtixSangstat)
minimizing infections without increasing graft-versus-host disease (GVHD) is unknown in T …

In haploidentical peripheral blood stem cell transplantation (haplo-PBSCT), the combination
of anti-thymocyte globulin and post-transplant cyclophosphamide (ATG/PTCy) has a …

HSCT is a therapeutic procedure that can cure and/or prolong life in a broad range of
hematologic disorders including malignant and nonmalignant pathologies. Conditioning is …

Adeno-associated virus (AAV) vector gene therapy is a promising treatment for a variety of
genetic diseases, including hemophilia. Systemic administration of AAV vectors is …

BACKGROUND Graft‐versus‐host disease (GVHD) is a major complication after allogeneic
hematopoietic stem cell transplantation (allo‐HSCT). Addition of antithymocyte globulin …