Signaling pathways in brain ischemia: Mechanisms and therapeutic implications

W Lin, XY Zhao, J Cheng, L Li, Q Jiang… - Pharmacology & …, 2023 - Elsevier
Ischemic stroke occurs when the arteries supplying blood to the brain are narrowed or
blocked, inducing damage to brain tissue due to a lack of blood supply. One effective way to …

Acupuncture treatment for post-stroke depression: Intestinal microbiota and its role

H Jiang, S Deng, J Zhang, J Chen, B Li… - Frontiers in …, 2023 - frontiersin.org
Stroke-induced depression is a common complication and an important risk factor for
disability. Besides psychiatric symptoms, depressed patients may also exhibit a variety of …

The immunopathology of B lymphocytes during stroke-induced injury and repair

MK Malone, TA Ujas, DRS Britsch, KM Cotter… - Seminars in …, 2023 - Springer
B cells, also known as B lymphocytes or lymphoid lineage cells, are a historically
understudied cell population with regard to brain-related injuries and diseases. However, an …

[HTML][HTML] CCR2+ monocytes replenish border-associated macrophages in the diseased mouse brain

L Wang, J Zheng, S Zhao, Y Wan, M Wang, DB Bosco… - Cell reports, 2024 - cell.com
Border-associated macrophages (BAMs) are tissue-resident macrophages that reside at the
border of the central nervous system (CNS). Since BAMs originate from yolk sac progenitors …

[HTML][HTML] T-cell receptor signaling modulated by the co-receptors: Potential targets for stroke treatment

Y Liu, S Chen, S Liu, KL Wallace, M Zille… - Pharmacological …, 2023 - Elsevier
Stroke is a severe and life-threatening disease, necessitating more research on new
treatment strategies. Infiltrated T lymphocytes, an essential adaptive immune cell with …

Interleukins in epilepsy: friend or foe

Y Dong, X Zhang, Y Wang - Neuroscience Bulletin, 2024 - Springer
Epilepsy is a chronic neurological disorder with recurrent unprovoked seizures, affecting~
65 million worldwide. Evidence in patients with epilepsy and animal models suggests a …

The immunomodulatory mechanism of acupuncture treatment for ischemic stroke: research progress, prospects, and future direction

H Kuang, X Zhu, H Chen, H Tang, H Zhao - Frontiers in Immunology, 2024 - frontiersin.org
Ischemic stroke (IS) is one of the leading causes of death and disability. Complicated
mechanisms are involved in the pathogenesis of IS. Immunomodulatory mechanisms are …

Chemokine CXCL13–CXCR5 signaling in neuroinflammation and pathogenesis of chronic pain and neurological diseases

K Zheng, M Chen, X Xu, P Li, C Yin, J Wang… - Cellular & Molecular …, 2024 - Springer
Chronic pain dramatically affects life qualities of the sufferers. It has posed a heavy burden
to both patients and the health care system. However, the current treatments for chronic pain …

[HTML][HTML] The role of JAK/STAT signaling pathway in cerebral ischemia-reperfusion injury and the therapeutic effect of traditional Chinese medicine: a narrative review

T Song, Y Zhang, L Zhu, Y Zhang, J Song - Medicine, 2023 - journals.lww.com
Cerebral ischemia is a cerebrovascular disease with symptoms caused by insufficient blood
or oxygen supply to the brain. When blood supplied is restored after cerebral ischemia …

Updates of the role of B-cells in ischemic stroke

S Wu, S Tabassum, CT Payne, H Hu… - Frontiers in Cellular …, 2024 - frontiersin.org
Ischemic stroke is a major disease causing death and disability in the elderly and is one of
the major diseases that seriously threaten human health and cause a great economic …