Trends in insulin resistance: insights into mechanisms and therapeutic strategy

M Li, X Chi, Y Wang, S Setrerrahmane… - Signal transduction and …, 2022 - nature.com
The centenary of insulin discovery represents an important opportunity to transform diabetes
from a fatal diagnosis into a medically manageable chronic condition. Insulin is a key …

[HTML][HTML] Nanotechnology-based drug delivery for central nervous system disorders

TT Nguyen, TTD Nguyen, TK Vo, MK Nguyen… - Biomedicine & …, 2021 - Elsevier
Drug delivery to central nervous system (CNS) diseases is very challenging since the
presence of the innate blood–brain barrier (BBB) and the blood-cerebrospinal fluid barrier …

The regulatory role of IL-10 in neurodegenerative diseases

C Porro, A Cianciulli, MA Panaro - Biomolecules, 2020 - mdpi.com
IL-10, an immunosuppressive cytokine, is considered an important anti-inflammatory
modulator of glial activation, preventing inflammation-mediated neuronal degeneration …

Memory and brain amyloid and tau effects of a bioavailable form of curcumin in non-demented adults: a double-blind, placebo-controlled 18-month trial

GW Small, P Siddarth, Z Li, KJ Miller, L Ercoli… - The American Journal of …, 2018 - Elsevier
Objective Because curcumin's anti-inflammatory properties may protect the brain from
neurodegeneration, we studied its effect on memory in non-demented adults and explored …