The stimulator of interferon genes (STING) cellular signaling pathway is a promising target
for cancer immunotherapy. Activation of the intracellular STING protein triggers the …

Immunotherapy has efficiently revolutionized the treatment of human neoplastic diseases.
However, the overall responsive rate of current immunotherapy is still unsatisfactory …

Radiation therapy (RT) activates an in situ vaccine effect when combined with immune
checkpoint blockade (ICB), yet this effect may be limited because RT does not fully optimize …

The current pandemic highlights the need for effective vaccines against respiratory viruses.
An ideal vaccine should induce robust and long-lasting responses with high manufacturing …

Traditional approaches to cancer vaccines elicit weak CD8+ T cell responses and have
largely failed to meet clinical expectations. This is in part due to inefficient antigen cross …

The gastrointestinal tract is lined by an epithelial monolayer responsible for selective
permeability and absorption, as well as protection against harmful luminal contents …

The clinical translation of many biomolecular therapeutics has been hindered by
undesirable pharmacokinetic (PK) properties, inadequate membrane permeability, poor …

Simple Summary The current standard of care for locally advanced melanoma is surgery first
followed by systemic therapy. However, there is growing evidence that neoadjuvant therapy …

Although the impacts of Saccharomyces cerevisiae on cancers are mentioned, data on its
use in mice with cyclic GMP-AMP synthase deficiency (cGAS-/-) are even rarer. Here, 12 …

The incidence of human herpesvirus (HHVs) is gradually increasing and has affected a wide
range of population. HHVs can result in serious consequences such as tumors, neonatal …