The lung in rheumatoid arthritis: focus on interstitial lung disease

P Spagnolo, JS Lee, N Sverzellati… - Arthritis & …, 2018 - Wiley Online Library
Interstitial lung disease (ILD) is an increasingly recognized complication of rheumatoid
arthritis (RA) and is associated with significant morbidity and mortality. In addition …

Synovial tissue research: a state-of-the-art review

C Orr, E Vieira-Sousa, DL Boyle, MH Buch… - Nature Reviews …, 2017 - nature.com
The synovium is the major target tissue of inflammatory arthritides such as rheumatoid
arthritis. The study of synovial tissue has advanced considerably throughout the past few …

Rheumatoid arthritis disease activity measures: American College of Rheumatology recommendations for use in clinical practice

J Anderson, L Caplan, J Yazdany… - Arthritis care & …, 2012 - Wiley Online Library
Objective Although the systematic measurement of disease activity facilitates clinical
decision making in rheumatoid arthritis (RA), no recommendations currently exist on which …

Treating rheumatoid arthritis to target: recommendations of an international task force

JS Smolen, D Aletaha, JWJ Bijlsma… - Annals of the …, 2010 - ard.bmj.com
Background Aiming at therapeutic targets has reduced the risk of organ failure in many
diseases such as diabetes or hypertension. Such targets have not been defined for …

Mortality in rheumatoid arthritis: the impact of disease activity, treatment with glucocorticoids, TNFα inhibitors and rituximab

J Listing, J Kekow, B Manger, GR Burmester… - Annals of the rheumatic …, 2015 - Elsevier
Objectives To investigate the impact of disease activity, the course of the disease, its
treatment over time, comorbidities and traditional risk factors on survival. Methods Data of …

STAT4 and the Risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus

EF Remmers, RM Plenge, AT Lee… - … England Journal of …, 2007 - Mass Medical Soc
Background Rheumatoid arthritis is a chronic inflammatory disease with a substantial
genetic component. Susceptibility to disease has been linked with a region on chromosome …

[PDF][PDF] Measures of functional status and quality of life in rheumatoid arthritis: health assessment questionnaire disability index (HAQ), modified health assessment …

L Maska, J Anderson, K Michaud - Arthritis care & research, 2011 - academia.edu
Purpose. Sometimes referred to as the HAQ DI, original, or “legacy” HAQ, the HAQ was
developed to assess functional status in adults with arthritis, but is now commonly used …

TRAF1–C5 as a Risk Locus for Rheumatoid Arthritis — A Genomewide Study

RM Plenge, M Seielstad, L Padyukov… - … England Journal of …, 2007 - Mass Medical Soc
Background Rheumatoid arthritis has a complex mode of inheritance. Although HLA-DRB1
and PTPN22 are well-established susceptibility loci, other genes that confer a modest level …

Improvement in 5-year mortality in incident rheumatoid arthritis compared with the general population—closing the mortality gap

D Lacaille, JA Avina-Zubieta, EC Sayre… - Annals of the rheumatic …, 2017 - Elsevier
Objective Excess mortality in rheumatoid arthritis (RA) is expected to have improved over
time, due to improved treatment. Our objective was to evaluate secular 5-year mortality …

[PDF][PDF] Mortality in rheumatoid arthritis: 2008 update

T Sokka, B Abelson, T Pincus - Clin Exp Rheumatol, 2008 - clinexprheumatol.org
Mortality rates in patients with rheumatoid arthritis (RA) are 1.5-1.6 fold higher than in the
general population, with similar patterns over 60 years. The acute attributed causes of death …