[HTML][HTML] Current Non-Viral-Based Strategies to Manufacture CAR-T Cells

L Gehrke, VDR Gonçalves, D Andrae, T Rasko… - International journal of …, 2024 - mdpi.com
The successful application of CAR-T cells in the treatment of hematologic malignancies has
fundamentally changed cancer therapy. With increasing numbers of registered CAR-T cell …

Efficient intracellular delivery of CRISPR-Cas9 ribonucleoproteins using dendrimer nanoparticles for robust genomic editing

W Liyanage, GR Kannan, S Kannan, RM Kannan - Nano Today, 2025 - Elsevier
CRISPR-Cas9, a flexible and efficient genome editing technology, is currently limited by the
challenge of delivering the large ribonucleoprotein complex intracellularly and into the …

CRISPR-Cas9 Gene Therapy: Non-Viral Delivery and Stimuli-Responsive Nanoformulations

H Lee, WY Rho, YH Kim, H Chang, BH Jun - Molecules, 2025 - mdpi.com
The CRISPR-Cas9 technology, one of the groundbreaking genome editing methods for
addressing genetic disorders, has emerged as a powerful, precise, and efficient tool …