The transport of specific molecules across lipid membranes is an essential function of all
living organisms and a large number of specific transporters have evolved to carry out this …

Cardiovascular diseases (CVDs) are one of the leading causes of the most considerable
mortality globally, and it has been tried to find the molecular mechanisms and design new …

High-density lipoproteins (HDL) have many biological functions, including reducing
endothelial activation and adhesion molecule expression. We recently reported that HDL …

Selection of the translational initiation site in most eukaryotic mRNAs appears to occur via a
scanning mechanism which predicts that proximity to the 5′ end plays a dominant role in …

Several nuclear hormone receptors involved in lipid metabolism form obligate heterodimers
with retinoid X receptors (RXRs) and are activated by RXR agonists such as rexinoids …

The maintenance of cellular cholesterol homeostasis is essential for normal cell function and
viability. Excessive cholesterol accumulation is detrimental to cells and serves as the …

Foam cell formation and further accumulation in the subendothelial space of the vascular
wall is a hallmark of atherosclerotic lesions. Targeting foam cell formation in the …

High-density lipoproteins (HDL) possess key atheroprotective biological properties,
including cellular cholesterol efflux capacity, and anti-oxidative and anti-inflammatory …

Research into lipoprotein metabolism has developed because understanding lipoprotein
metabolism has important clinical indications. Lipoproteins are risk factors for cardiovascular …

Multiple human population studies have established the concentration of high density
lipoprotein (HDL) cholesterol as an independent, inverse predictor of the risk of having a …