Drug addiction is a chronically relapsing disorder characterized by loss of control over intake
and dysregulation of stress-related brain emotional systems. Since the discovery by Wylie …

The eponymous term nucleus of Edinger‐Westphal (EW) has come to be used to describe
two juxtaposed and somewhat intermingled cell groups of the midbrain that differ …

Urocortins, three paralogs of the stress-related peptide corticotropin-releasing factor (CRF)
found in bony fish, amphibians, birds, and mammals, have unique phylogenies …

Major depressive disorder (MDD) is a devastating disease affecting over 300 million people
worldwide, and costing an estimated 380 billion Euros in lost productivity and health care in …

Many neuronal populations that release fast-acting excitatory and inhibitory
neurotransmitters in the brain also contain slower-acting neuropeptides. These facultative …

Recent evidence suggests a role for corticotropin-releasing factor (CRF) in the regulation of
pair bonding in prairie voles. We have previously shown that monogamous and non …

Central stress regulatory pathways utilize various neuropeptides, such as urocortin-1 (Ucn1)
and cocaine-and amphetamine-regulated transcript peptide (CART). Ucn1 is most …

Exposure to prenatal stress (PS) leads to the offspring's vulnerability towards the
development of cognitive and behavioral disorders. Laterodorsal tegmentum (LDT) is a part …

Genetically modified mice are used to study the neurobiological basis of normal behavior
and have been developed as models of human neurodegenerative and psychiatric …

Urocortin is a member of the corticotropin-releasing hormone (CRH) family of peptides. In
the brain, its potent suppression of food intake is mediated by CRH receptors (CRHR) …