Reading the repertoire: Progress in adaptive immune receptor analysis using machine learning
The adaptive immune system holds invaluable information on past and present immune
responses in the form of B and T cell receptor sequences, but we are limited in our ability to …
responses in the form of B and T cell receptor sequences, but we are limited in our ability to …
Next-generation therapeutic antibodies for cancer treatment: advancements, applications, and challenges
The field of cancer treatment has evolved significantly over the last decade with the
emergence of next-generation therapeutic antibodies. Conventional treatments like …
emergence of next-generation therapeutic antibodies. Conventional treatments like …
AIntibody: an experimentally validated in silico antibody discovery design challenge
Science is frequently subject to the Gartner hype cycle 1: emergent technologies spark
intense initial enthusiasm with the recruitment of dedicated scientists. As limitations are …
intense initial enthusiasm with the recruitment of dedicated scientists. As limitations are …
[HTML][HTML] The Application of Machine Learning on Antibody Discovery and Optimization
J Zheng, Y Wang, Q Liang, L Cui, L Wang - Molecules, 2024 - mdpi.com
Antibodies play critical roles in modern medicine, serving as diagnostics and therapeutics
for various diseases due to their ability to specifically bind to target antigens. Traditional …
for various diseases due to their ability to specifically bind to target antigens. Traditional …
Digital Transformation in the Biopharmaceutical Industry: Rebuilding the Way We Discover Complex Therapeutics
The biopharmaceutical sector, driven by the possibility of curing diseases, has made
tremendous progress over the last decades: the first biosynthetic human insulin in 1982; the …
tremendous progress over the last decades: the first biosynthetic human insulin in 1982; the …
The Artificial Intelligence Revolution: Transforming the Design and Optimization of Multispecific Antibodies
Artificial intelligence (AI) is rapidly transforming protein engineering, impacting our approach
to the development of therapeutic monoclonal antibodies (mAb). Industrial workflows for the …
to the development of therapeutic monoclonal antibodies (mAb). Industrial workflows for the …
[BOOK][B] Biopharmaceutical Informatics: Learning to Discover Developable Biotherapeutics
S Kumar, A Nixon - 2025 - books.google.com
Despite the phenomenal clinical success of antibody-based biopharmaceuticals in recent
years, discovery and development of these novel biomedicines remains a costly, time …
years, discovery and development of these novel biomedicines remains a costly, time …