Much progress has been made in the identification of specific human gene variants that
contribute to enhanced susceptibility or resistance to viral diseases. Herein we review …

For almost three decades following the discovery of the human Hepatitis B Virus (HBV) the
early events of virus infection (attachment to hepatocytes, specific binding to a receptor on …

Chronic infection with hepatitis B virus (HBV) affects more than 290 million people
worldwide, is a major cause of cirrhosis and hepatocellular carcinoma, and results in an …

Zoonotic avian influenza A virus (IAV) infections are rare. Sustained transmission of these
IAVs between humans has not been observed, suggesting a role for host genes. We used …

Hepatitis B virus (HBV), a leading cause of develo** hepatocellular carcinoma affecting
more than 290 million people worldwide, is an enveloped DNA virus specifically infecting …

Genomic research that targets large-scale, prospective birth cohorts constitutes an essential
strategy for understanding the influence of genetics and environment on human health …

Background & Aims One major obstacle of hepatitis B virus (HBV) research is the lack of
efficient cell culture system permissive for viral infection and replication. The aim of our study …

Objective The sodium taurocholate co-transporting polypeptide (NTCP), encoded by
SLC10A1, was recently identified as a receptor for HBV. We assessed the association of the …

Cellular entry of the hepatitis B and D viruses (HBV/HDV) requires binding of the viral
surface polypeptide preS1 to the hepatobiliary transporter Na+-taurocholate co-transporting …

Background We investigated the patterns and predictors for virological relapse (VR), clinical
relapse (CR), and sustained clinical response (SCR) and the outcomes of retreatment after …