Infection and telomere length: a systematic review protocol

L Tunnicliffe, R Muzambi, JW Bartlett, L Howe… - BMJ open, 2024 - bmjopen.bmj.com
Introduction Telomeres are a measure of cellular ageing with potential links to diseases
such as cardiovascular diseases and cancer. Studies have shown that some infections may …

HIV infection, chromosome instability, and micronucleus formation

JH Ellwanger, B Kulmann-Leal, M Ziliotto, JAB Chies - Viruses, 2023 - mdpi.com
Genome integrity is critical for proper cell functioning, and chromosome instability can lead
to age-related diseases, including cancer and neurodegenerative disorders. Chromosome …

The genetic architecture of bovine telomere length in early life and association with animal fitness

JJ Ilska-Warner, A Psifidi, LA Seeker… - Frontiers in …, 2019 - frontiersin.org
Health and survival are key goals for selective breeding in farm animals. Progress, however,
is often limited by the low heritability of these animal fitness traits in addition to measurement …

Monocyte/macrophage-mediated innate immunity in HIV-1 infection: from early response to late dysregulation and links to cardiovascular diseases onset

E Teer, DE Joseph, RH Glashoff, M Faadiel Essop - Virologica Sinica, 2021 - Springer
Although monocytes and macrophages are key mediators of the innate immune system, the
focus has largely been on the role of the adaptive immune system in the context of human …

[HTML][HTML] A multibreed genome-wide association study for cattle leukocyte telomere length

AV Igoshin, NS Yudin, GA Romashov, DM Larkin - Genes, 2023 - mdpi.com
Telomeres are terminal DNA regions of chromosomes that prevent chromosomal fusion and
degradation during cell division. In cattle, leukocyte telomere length (LTL) is associated with …

Telomere length, health, and mortality in a cohort of older black South African adults

S Gao, JK Rohr, I de Vivo, M Ramsay… - The Journals of …, 2023 - academic.oup.com
Telomere length (TL) may be a biomarker of aging processes as well as age-related
diseases. However, most studies of TL and aging are conducted in high-income countries …

Telomere length analysis from minimally‐invasively collected samples: Methods development and meta‐analysis of the validity of different sampling techniques …

PH Rej, MH Bondy, J Lin, AA Prather… - American Journal of …, 2021 - Wiley Online Library
Objectives Telomeres are the protective caps of chromosomes. They shorten with cell
replication, age, and possibly environmental stimuli (eg, infection and stress). Short telomere …

[HTML][HTML] Association between Combination Antiretroviral Therapy and Telomere Length in People Living with Human Immunodeficiency Virus

E Bukic, J Milasin, B Toljic, J Jadzic, D Jevtovic… - Biology, 2023 - mdpi.com
Simple Summary Inevitable aging is accompanied by progressive decline in vital functions.
People living with HIV infection may experience accelerated aging caused by constant state …

Impaired differentiation of small airway basal stem/progenitor cells in people living with HIV

NPY Chung, KMF Khan, M Andreoli, RJ Kaner… - Scientific Reports, 2022 - nature.com
With highly active anti-retroviral therapy (HAART), higher incidence of airway abnormalities
is common in the HIV population consistent with the concept of accelerated lung “aging”. Our …

The Impact of HIV and Parasite Single Infection and Coinfection on Telomere Length: A Systematic Review

ED Macamo, ZL Mkhize-Kwitshana… - Current Issues in …, 2024 - pmc.ncbi.nlm.nih.gov
HIV and parasite infections accelerate biological aging, resulting in immune senescence,
apoptosis and cellular damage. Telomere length is considered to be one of the most …