Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

MJ Chapman, HN Ginsberg, P Amarenco… - European heart …, 2011 - academic.oup.com
Even at low-density lipoprotein cholesterol (LDL-C) goal, patients with cardiometabolic
abnormalities remain at high risk of cardiovascular events. This paper aims (i) to critically …

Addressing dyslipidemic risk beyond LDL-cholesterol

AR Tall, DG Thomas… - The Journal of …, 2022 - Am Soc Clin Investig
Despite the success of LDL-lowering drugs in reducing cardiovascular disease (CVD), there
remains a large burden of residual disease due in part to persistent dyslipidemia …

Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus …

HN Ginsberg, CJ Packard, MJ Chapman… - European heart …, 2021 - academic.oup.com
Recent advances in human genetics, together with a large body of epidemiologic,
preclinical, and clinical trial results, provide strong support for a causal association between …

Triglycerides and cardiovascular disease: a scientific statement from the American Heart Association

M Miller, NJ Stone, C Ballantyne, V Bittner, MH Criqui… - Circulation, 2011 - Am Heart Assoc
A long-standing association exists between elevated triglyceride levels and cardiovascular
disease*(CVD). 1, 2 However, the extent to which triglycerides directly promote CVD or …

New insight into dyslipidemia‐induced cellular senescence in atherosclerosis

Q **ang, F Tian, J Xu, X Du, S Zhang… - Biological Reviews, 2022 - Wiley Online Library
Atherosclerosis, characterized by lipid‐rich plaques in the arterial wall, is an age‐related
disorder and a leading cause of mortality worldwide. However, the specific mechanisms …

Cardiovascular disease risk in type 2 diabetes mellitus: insights from mechanistic studies

T Mazzone, A Chait, J Plutzky - The Lancet, 2008 - thelancet.com
Individuals with type 2 diabetes mellitus have increased cardiovascular disease risk
compared with those without diabetes. Treatment of the residual risk, other than blood …

Engineering of a Hollow‐Structured Cu2−XS Nano‐Homojunction Platform for Near Infrared‐Triggered Infected Wound Healing and Cancer Therapy

X Gao, M Wei, D Ma, X Yang, Y Zhang… - Advanced Functional …, 2021 - Wiley Online Library
Infection and malignant tumors are the most common diseases in people's daily life, which
seriously threaten human health. Because of the frequent and extensive administration of …

The Residual Risk Reduction Initiative: a call to action to reduce residual vascular risk in patients with dyslipidemia

JC Fruchart, F Sacks, MP Hermans, G Assmann… - The American journal of …, 2008 - Elsevier
Despite achieving targets for low-density lipoprotein (LDL) cholesterol, blood pressure, and
glycemia in accordance with current standards of care, patients with dyslipidemia remain at …

Remnant cholesterol as a cause of ischemic heart disease: evidence, definition, measurement, atherogenicity, high risk patients, and present and future treatment

A Varbo, M Benn, BG Nordestgaard - Pharmacology & therapeutics, 2014 - Elsevier
This review focuses on remnant cholesterol as a causal risk factor for ischemic heart disease
(IHD), on its definition, measurement, atherogenicity, and levels in high risk patient groups; …

Postprandial lipemia and cardiovascular disease risk: Interrelationships between dietary, physiological and genetic determinants

KG Jackson, SD Poppitt, AM Minihane - Atherosclerosis, 2012 - Elsevier
Although the independence of the association and causality has not been fully established,
non-fasting (postprandial) triglyceride (TG) concentrations have emerged as a clinically …