[HTML][HTML] Promising bioactive compounds from the marine environment and their potential effects on various diseases

A Karthikeyan, A Joseph, BG Nair - Journal of Genetic Engineering and …, 2022 - Elsevier
Background The marine environment hosts a wide variety of species that have evolved to
live in harsh and challenging conditions. Marine organisms are the focus of interest due to …

Ecology and genomics of Actinobacteria: new concepts for natural product discovery

DA van Bergeijk, BR Terlouw, MH Medema… - Nature Reviews …, 2020 - nature.com
Actinobacteria constitute a highly diverse bacterial phylum with an unrivalled metabolic
versatility. They produce most of the clinically used antibiotics and a plethora of other natural …

AutoMLST: an automated web server for generating multi-locus species trees highlighting natural product potential

M Alanjary, K Steinke, N Ziemert - Nucleic Acids Research, 2019 - academic.oup.com
Understanding the evolutionary background of a bacterial isolate has applications for a wide
range of research. However generating an accurate species phylogeny remains …

Marine actinomycetes, new sources of biotechnological products

SV Jagannathan, EM Manemann, SE Rowe… - Marine Drugs, 2021 - mdpi.com
The Actinomycetales order is one of great genetic and functional diversity, including diversity
in the production of secondary metabolites which have uses in medical, environmental …

[HTML][HTML] An introduction to actinobacteria

R Anandan, D Dharumadurai… - Actinobacteria-basics …, 2016 - intechopen.com
Actinobacteria, which share the characteristics of both bacteria and fungi, are widely
distributed in both terrestrial and aquatic ecosystems, mainly in soil, where they play an …

Taxonomy, physiology, and natural products of Actinobacteria

EA Barka, P Vatsa, L Sanchez… - Microbiology and …, 2016 - Am Soc Microbiol
Actinobacteria are Gram-positive bacteria with high G+ C DNA content that constitute one of
the largest bacterial phyla, and they are ubiquitously distributed in both aquatic and …

A roadmap for natural product discovery based on large-scale genomics and metabolomics

JR Doroghazi, JC Albright, AW Goering, KS Ju… - Nature chemical …, 2014 - nature.com
Actinobacteria encode a wealth of natural product biosynthetic gene clusters, whose
systematic study is complicated by numerous repetitive motifs. By combining several metrics …

[HTML][HTML] Pharmaceutically active secondary metabolites of marine actinobacteria

P Manivasagan, J Venkatesan, K Sivakumar… - Microbiological …, 2014 - Elsevier
Marine actinobacteria are one of the most efficient groups of secondary metabolite
producers and are very important from an industrial point of view. Many representatives of …

Microbial natural products in drug discovery

AS Abdel-Razek, ME El-Naggar, A Allam, OM Morsy… - Processes, 2020 - mdpi.com
Over a long period of time, humans have explored many natural resources looking for
remedies of various ailments. Traditional medicines have played an intrinsic role in human …

[HTML][HTML] Marine actinomycetes: an ongoing source of novel bioactive metabolites

R Subramani, W Aalbersberg - Microbiological research, 2012 - Elsevier
Actinomycetes are virtually unlimited sources of novel compounds with many therapeutic
applications and hold a prominent position due to their diversity and proven ability to …