Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies
Manganese (Mn) is an essential heavy metal. However, Mn's nutritional aspects are
paralleled by its role as a neurotoxicant upon excessive exposure. In this review, we …
paralleled by its role as a neurotoxicant upon excessive exposure. In this review, we …
Manganese-induced neurotoxicity: new insights into the triad of protein misfolding, mitochondrial impairment, and neuroinflammation
Occupational or environmental exposure to manganese (Mn) can lead to the development of
“Manganism,” a neurological condition showing certain motor symptoms similar to …
“Manganism,” a neurological condition showing certain motor symptoms similar to …
Acetylcholinesterase inhibitors in the treatment of neurodegenerative diseases and the role of acetylcholinesterase in their pathogenesis
ŁJ Walczak-Nowicka, M Herbet - International journal of molecular …, 2021 - mdpi.com
Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …
Manganese in health and disease
Manganese is an important metal for human health, being absolutely necessary for
development, metabolism, and the antioxidant system. Nevertheless, excessive exposure or …
development, metabolism, and the antioxidant system. Nevertheless, excessive exposure or …
Organophosphate toxicity: Updates of malathion potential toxic effects in mammals and potential treatments
AM Badr - Environmental science and pollution research, 2020 - Springer
Organophosphorus insecticides toxicity is still considered a major global health problem.
Malathion is one of the most commonly used organophosphates nowadays, as being …
Malathion is one of the most commonly used organophosphates nowadays, as being …
Consequences of disturbing manganese homeostasis
Manganese (Mn) is an essential trace element with unique functions in the body; it acts as a
cofactor for many enzymes involved in energy metabolism, the endogenous antioxidant …
cofactor for many enzymes involved in energy metabolism, the endogenous antioxidant …
Redox dynamics of manganese as a mitochondrial life-death switch
Abstract Sten Orrenius, MD, Ph. D., pioneered many areas of cellular and molecular
toxicology and made seminal contributions to our knowledge of oxidative stress and …
toxicology and made seminal contributions to our knowledge of oxidative stress and …
New insights into manganese toxicity and speciation
B Michalke, K Fernsebner - Journal of Trace Elements in Medicine and …, 2014 - Elsevier
Manganese (Mn) is known to be a neurotoxic agent for nearly 175 years now. A lot of
research has therefore been carried out over the last century. From preliminary describing …
research has therefore been carried out over the last century. From preliminary describing …
Manganese accumulation in the brain via various transporters and its neurotoxicity mechanisms
Manganese (Mn) is an essential trace element, serving as a cofactor for several key
enzymes, such as glutamine synthetase, arginase, pyruvate decarboxylase, and …
enzymes, such as glutamine synthetase, arginase, pyruvate decarboxylase, and …
New insights on the role of manganese in Alzheimer's disease and Parkinson's disease
Manganese (Mn) is an essential trace element that is naturally found in the environment and
is necessary as a cofactor for many enzymes and is important in several physiological …
is necessary as a cofactor for many enzymes and is important in several physiological …